MLB

Chicago Cubs at Cincinnati Reds – Where to Watch, Stream Info, TV Channel, and Live Updates (September 21, 2025)

September 21, 2025 by Fubo Sports Desk
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The Chicago Cubs (88-67) are set to face the Cincinnati Reds (79-76) in a pivotal matchup at Great American Ball Park. The Cubs enter the game on a three-game losing streak, while the Reds are riding a four-game winning streak, showcasing a stark contrast in recent performance. Chicago holds a winning percentage of .568, ranking second in their division, while Cincinnati’s winning percentage stands at .510, placing them third. Key players for the Cubs include Nico Hoerner, who leads the team with a .301 batting average, and Seiya Suzuki, who has driven in 91 runs. For the Reds, Elly De La Cruz stands out with 100 runs scored and 83 RBIs. Both teams will look to capitalize on their respective strengths as they vie for crucial wins in the closing weeks of the season.

Chicago Cubs at Cincinnati Reds Game Information

Game Date: September 21, 2025
Game Time: 01:40 PM ET
TV Channel: FanDuel Sports Network Indiana, Marquee Sports Network
Location: Great American Ball Park, Cincinnati, OH
Live Stream: Fubo (free trial)

Live Updates

5:04 PM ET
Pete Crow-Armstrong called out on strikes.
5:01 PM ET
Michael Busch walks. Moisés Ballesteros to second.
4:59 PM ET
Willi Castro strikes out swinging.
4:56 PM ET
Willi Castro pinch-hitting for Justin Turner.
4:56 PM ET
Dansby Swanson flies out to right center field to Noelvi Marte.
4:55 PM ET
Moisés Ballesteros walks.
4:52 PM ET
Tony Santillan (P) replaces Graham Ashcraft (P).
4:51 PM ET
Gavin Lux grounds out to second base, Nico Hoerner to Michael Busch.
4:50 PM ET
TJ Friedl flies out to left field to Ian Happ.
4:48 PM ET
Matt McLain called out on strikes.
4:46 PM ET
Brad Keller (P) replaces Jameson Taillon (P).
4:46 PM ET
Carson Kelly pops out to Jose Trevino.
4:43 PM ET
Seiya Suzuki singles to shallow right field.
4:41 PM ET
Ian Happ strikes out swinging.
4:40 PM ET
Nico Hoerner pops out to shortstop to Elly De La Cruz.
4:38 PM ET
Graham Ashcraft (P) replaces Nick Martinez (P).
4:37 PM ET
Jose Trevino grounds out to shallow infield, Jameson Taillon to Michael Busch.
4:36 PM ET
Ke'Bryan Hayes flies out to center field to Pete Crow-Armstrong.
4:31 PM ET
Elly De La Cruz singles to center field.
4:31 PM ET
Will Benson pops out to shallow left field to Dansby Swanson.
4:30 PM ET
Pete Crow-Armstrong remains in the game as CF.
4:27 PM ET
Pete Crow-Armstrong flies out to deep center field to TJ Friedl.
4:25 PM ET
Pete Crow-Armstrong pinch-hitting for Kevin Alcántara.
4:25 PM ET
Michael Busch flies out to deep center field to TJ Friedl.
4:24 PM ET
Justin Turner grounds out to shortstop, Ke'Bryan Hayes to Spencer Steer.
4:20 PM ET
Spencer Steer strikes out swinging.
4:18 PM ET
Noelvi Marte hits into a force out to third base. Gavin Lux out at second.
4:17 PM ET
Gavin Lux singles to right field.
4:16 PM ET
TJ Friedl strikes out swinging.
4:14 PM ET
Moisés Ballesteros remains in the game as DH.
4:13 PM ET
Dansby Swanson flies out to shallow right field to Matt McLain.
4:11 PM ET
Moisés Ballesteros lines out to deep center field to TJ Friedl.
4:10 PM ET
Moisés Ballesteros pinch-hitting for Carlos Santana.
4:09 PM ET
Carson Kelly grounds out to second base to Spencer Steer.
4:05 PM ET
Matt McLain flies out to deep center field to Kevin Alcántara.
4:04 PM ET
Jose Trevino flies out to left field to Ian Happ.
4:04 PM ET
Ke'Bryan Hayes called out on strikes.
4:01 PM ET
Seiya Suzuki strikes out swinging.
3:57 PM ET
Nick Martinez (P) replaces Andrew Abbott (P).
3:56 PM ET
Ian Happ singles to right center field.
3:55 PM ET
Nico Hoerner pops out to shallow infield to Matt McLain.
3:54 PM ET
Kevin Alcántara lines out to shortstop to Elly De La Cruz.
3:52 PM ET
Elly De La Cruz grounds out to second base, Nico Hoerner to Michael Busch.
3:49 PM ET
Will Benson grounds out to first base, Michael Busch to Jameson Taillon.
3:48 PM ET
Spencer Steer grounds out to shallow left field, Dansby Swanson to Michael Busch.
3:44 PM ET
Michael Busch pops out to Ke'Bryan Hayes.
3:42 PM ET
Justin Turner flies out to deep center field to TJ Friedl. Carlos Santana to third.
3:42 PM ET
Dansby Swanson singles to center field. Carlos Santana to second.
3:40 PM ET
Carlos Santana singles to deep left field.
3:38 PM ET
Carson Kelly called out on strikes.
3:35 PM ET
Noelvi Marte pops out to Carson Kelly.
3:33 PM ET
Gavin Lux doubles to deep right field. Matt McLain scores.
3:32 PM ET
TJ Friedl flies out to center field to Kevin Alcántara.
3:31 PM ET
Matt McLain doubles to deep left field.
3:30 PM ET
Jose Trevino lines out to deep left field to Ian Happ.
3:27 PM ET
Seiya Suzuki flies out to center field to TJ Friedl.
3:26 PM ET
Ian Happ pops out to shallow infield to Ke'Bryan Hayes.
3:23 PM ET
Nico Hoerner lines out to right center field to TJ Friedl.
3:21 PM ET
Kevin Alcántara singles to left center field. Michael Busch to second.
3:19 PM ET
Michael Busch singles to shallow right field.
3:16 PM ET
Ke'Bryan Hayes grounds out to shortstop, Dansby Swanson to Michael Busch.
3:15 PM ET
Elly De La Cruz strikes out on a foul tip.
3:14 PM ET
Will Benson grounds out to first base, Michael Busch to Jameson Taillon.
3:11 PM ET
Justin Turner grounds out to shortstop, Ke'Bryan Hayes to Spencer Steer.
3:10 PM ET
Dansby Swanson hits into a force out to shallow infield. Carson Kelly out at second.
3:09 PM ET
Carlos Santana lines out to deep left field to Will Benson.
3:07 PM ET
Carson Kelly walks.
3:02 PM ET
Spencer Steer flies out to shallow center field to Seiya Suzuki.
3:01 PM ET
Noelvi Marte singles to left field.
3:00 PM ET
Gavin Lux grounds out to second base, Jameson Taillon to Nico Hoerner to Michael Busch.
2:59 PM ET
TJ Friedl grounds out to shallow infield, Jameson Taillon to Michael Busch.
2:55 PM ET
Seiya Suzuki flies out to right field to Noelvi Marte.
2:54 PM ET
Ian Happ strikes out swinging.
2:52 PM ET
Nico Hoerner lines out to right field to Noelvi Marte.

Cincinnati Reds Team Statistics and Rankings

Win-Loss Record: 79-76
Home Record: 43-34
Away Record: 36-42
Division Record: 22-23
Streak: 4 Win streak
Winning Percentage: .510

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Chicago Cubs Team Statistics and Rankings

Win-Loss Record: 88-67
Home Record: 46-29
Away Record: 42-38
Division Record: 27-21
Streak: 3 Loss streak
Winning Percentage: .568

Stat Leaders

Cincinnati Reds (79-76, #3 in division)

Batting Average Leader: Austin Wynns, 0.400
RBI Leader: Elly De La Cruz, 83 RBI
Home Run Leader: Spencer Steer, 21 HR
Runs Leader: Elly De La Cruz, 100 Runs
Hits Leader: Elly De La Cruz, 158 Hits
Stolen Bases Leader: Elly De La Cruz, 36 SB
ERA Leader: Tony Santillan, 2.46 ERA
Strikeout Leader: Brady Singer, 155 K
Wins Leader: Brady Singer, 14 W
Saves Leader: Emilio Pagán, 29 SV

Chicago Cubs (88-67, #2 in division)

Batting Average Leader: Nico Hoerner, 0.301
RBI Leader: Seiya Suzuki, 91 RBI
Home Run Leader: Michael Busch, 30 HR
Runs Leader: Kyle Tucker, 89 Runs
Hits Leader: Nico Hoerner, 171 Hits
Stolen Bases Leader: Pete Crow-Armstrong, 35 SB
ERA Leader: Michael Soroka, 1.80 ERA
Strikeout Leader: Matthew Boyd, 151 K
Wins Leader: Matthew Boyd, 13 W
Saves Leader: Daniel Palencia, 22 SV

Cincinnati Reds Injury Report

Carson Spiers – Shoulder (D60) – The Cincinnati Reds transferred RHP Carson Spiers from the 15-day injured list to the 60-day injured list as he recovers from a right shoulder impingement.
Julian Aguiar – Elbow (D60) – The Cincinnati Reds placed RHP Julian Aguiar on the 60-day injured list as he recovers from Tommy John surgery. Aguiar will miss the entire 2025 season after undergoing Tommy John surgery, Mark Sheldon of MLB.com reports.
Ian Gibaut – Shoulder (D60) – The Cincinnati Reds transferred RHP Ian Gibaut from the 15-day injured list to the 60-day injured list with a right shoulder impingement.
Wade Miley – Flexor (D60) – The Cincinnati Reds transferred LHP Wade Miley from the 15-day injured list to the 60-day injured list with a flexor strain.
Tyler Callihan – Forearm (D60) – The Cincinnati Reds placed INF Tyler Callihan on the 60-day injured list with a left forearm fracture.
Rhett Lowder – Forearm (D60) – The Cincinnati Reds transferred RHP Rhett Lowder from the 15-day injured list to the 60-day injured list with a right forearm strain.
Brandon Williamson – Elbow (D60) – The Cincinnati Reds placed LHP Brandon Williamson on the 60-day injured list with a left elbow strain.
Austin Hays – Back (Day-to-Day) – Hays left Saturday’s (Sept. 20) game against the Cubs due to back spasms.

Chicago Cubs Injury Report

Miguel Amaya – Ankle (D10) – The Chicago Cubs placed C Miguel Amaya on the 10-day injured list with a left ankle sprain.
Owen Caissie – Concussion (D7) – The Chicago Cubs placed OF Owen Caissie on the 7-day injured list.
Daniel Palencia – Shoulder (D15) – The Chicago Cubs placed RHP Daniel Palencia on the 15-day injured list with right shoulder strain.
Ryan Brasier – Groin (D15) – The Chicago Cubs placed RHP Ryan Brasier on the 15-day injured list with a left groin strain.
Justin Steele – Elbow (D60) – The Chicago Cubs transferred LHP Justin Steele from the 15-day injured list to the 60-day injured list and will undergo season-ending surgery to repair his flexor tendon and address UCL damage in his left elbow.
Kyle Tucker – Calf (D10) – The Chicago Cubs placed OF Kyle Tucker on the 10-day injured list due to a left calf strain.

Cincinnati Reds Upcoming 2025 Schedule

September 21, 2025 vs Chicago Cubs
September 23, 2025 vs Pittsburgh Pirates
September 24, 2025 vs Pittsburgh Pirates
September 25, 2025 vs Pittsburgh Pirates
September 26, 2025 at Milwaukee Brewers
September 27, 2025 at Milwaukee Brewers
September 28, 2025 at Milwaukee Brewers

Chicago Cubs Upcoming 2025 Schedule

September 21, 2025 at Cincinnati Reds
September 23, 2025 vs New York Mets
September 24, 2025 vs New York Mets
September 25, 2025 vs New York Mets
September 26, 2025 vs St. Louis Cardinals
September 27, 2025 vs St. Louis Cardinals
September 28, 2025 vs St. Louis Cardinals

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