How to Watch Giants at Padres (Aug. 21): Stream MLB Live, TV Channel

Justin Verlander and the San Francisco Giants will close out a four-game series against Dylan Cease and the San Diego Padres on Thursday afternoon.

The San Francisco Giants will stay on the road this week to take on the San Diego Padres at Petco Park in on Thursday afternoon for the fourth and final game of a four-game series. The Padres have won two of the three games of this series and will look to hang on and clinch the series win with a win tonight. They also lead the season series 4-1 heading into the last game. The Giants won the first game of the series, 4-3, on the back of home runs from Rafael Devers, Wilmer Flores, and Heliot Ramos, with Flores as the only two-run shot.

How to Watch San Francisco Giants at San Diego Padres Today:

Game Date: Thursday, Aug. 21, 2025

Game Time: 4:10 p.m. ET

TV Channel: MLB.TV – San Diego Padres, NBC Sports Bay Area, San Diego Padres (NEW)

Location: Petco Park

Live stream San Francisco Giants at San Diego Padres on Fubo: Start Watching Today!

Heading into the second game, San Diego pulled away with a 5-1 win as Nick Pivetta struck out 10 batters over six innings, giving up just one earned run on three hits. Five different players had a single RBI in that win. Yesterday, San Diego again only allowed one run, winning 8-1. Gavin Sheets hit two out of the park with four RBIs on just two hits on the night. Manny Machado and Ryan O’Hearn also had home runs.

Justin Verlander will be the first on the mound in this last game for San Francisco. The right-hander is 1-9 in decided starts this season with a 4.23 ERA and a 1.42 WHIP. The starting pitcher has 95 strikeouts over 106.1 innings, while only conceding 115 hits. Verlander’s last start came against the Tampa Bay Rays, where his team lost 2-1. He pitched a scoreless seven innings, giving up only two hits with eight strikeouts.

San Diego will counter San Francisco’s bats by putting Dylan Cease back on the mound tonight. The right-hander is 5-11 in his 2025 campaign with a 4.61 ERA and a 1.31 WHIP. He has given up 118 hits over 132.2 innings with 171 strikeouts. Cease gave up three earned runs on two hits against the Los Angeles Dodgers in his last start. He struck out just two batters across 3.1 innings.

What Time Is The MLB Game Between San Francisco and San Diego On?

The San Francisco Giants at San Diego Padres game will take place on Thursday, August 21, 2025, at 4:10 p.m. ET. Tune in and catch some great Major League Baseball action.

What Channel Is The San Francisco Giants at San Diego Padres Game On?

Looking to watch this game? Fans in the San Diego and San Francisco areas can tune into NBC Sports Bay Area and San Diego Padres (NEW) to see the action. Make sure you subscribe to Fubo now to watch this match and many other baseball games.

Live stream San Francisco Giants at San Diego Padres on Fubo: Start Watching Today!

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