MLB

San Diego Padres at Chicago White Sox – Where to Watch, Stream Info, TV Channel, and Live Updates (September 21, 2025)

September 21, 2025 by Fubo Sports Desk
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The San Diego Padres, holding a record of 84-71, are set to face the Chicago White Sox, who sit at 58-97, in a matchup at Rate Field. The Padres are currently on a one-game winning streak, while the White Sox are experiencing a one-game losing streak. San Diego has performed well on the road with a 37-43 record, while Chicago has struggled at home, posting a 33-47 record. Key players for the Padres include Manny Machado, who leads the team with 93 RBIs and 26 home runs, and Mason Miller, boasting an impressive 0.89 ERA. The White Sox’s Lenyn Sosa leads his team with 71 RBIs and 21 home runs. This game presents a critical opportunity for the Padres to solidify their playoff positioning against a struggling White Sox squad.

San Diego Padres at Chicago White Sox Game Information

Game Date: September 21, 2025
Game Time: 02:10 PM ET
TV Channel: San Diego Padres, Chicago Sports Network, MLB.TV – Chicago White Sox
Location: Rate Field, Chicago, IL
Live Stream: Fubo (free trial)

Live Updates

4:53 PM ET
Miguel Vargas strikes out on a foul tip.
4:52 PM ET
Colson Montgomery grounds out to first base, Luis Arraez to Robert Suarez.
4:50 PM ET
Kyle Teel strikes out swinging.
4:49 PM ET
Robert Suarez (P) replaces Wandy Peralta (P).
4:49 PM ET
Freddy Fermin (C) replaces Will Wagner (PH), batting 9th.
4:49 PM ET
Jake Cronenworth switches from SS to 2B.
4:49 PM ET
Mason McCoy remains in the game as SS.
4:49 PM ET
Luis Arraez switches from 2B to 1B.
4:46 PM ET
Fernando Tatis strikes out swinging.
4:45 PM ET
Will Wagner flies out to shallow center field to Korey Lee.
4:43 PM ET
Will Wagner pinch-hitting for Elias Díaz.
4:41 PM ET
Jordan Leasure (P) replaces Brandon Eisert (P).
4:41 PM ET
Jake Cronenworth reaches on error. Mason McCoy to second. Fielding error by Korey Lee.
4:39 PM ET
Mason McCoy pinch-running for Ryan O'Hearn.
4:39 PM ET
Ryan O'Hearn singles to shallow center field.
4:37 PM ET
Gavin Sheets strikes out swinging.
4:35 PM ET
Brandon Eisert (P) replaces Grant Taylor (P).
4:34 PM ET
Chase Meidroth grounds out to shortstop. Dominic Fletcher out at second.
4:32 PM ET
Dominic Fletcher walks.
4:29 PM ET
Michael A. Taylor strikes out swinging.
4:27 PM ET
Wandy Peralta (P) replaces Mason Miller (P).
4:26 PM ET
Ramón Laureano called out on strikes.
4:24 PM ET
Jackson Merrill flies out to Korey Lee.
4:24 PM ET
Manny Machado strikes out swinging.
4:22 PM ET
Grant Taylor (P) replaces Mike Vasil (P).
4:22 PM ET
Korey Lee remains in the game as LF.
4:22 PM ET
Miguel Vargas switches from LF to 3B.
4:20 PM ET
Lenyn Sosa grounds out to shortstop, Manny Machado to Ryan O'Hearn.
4:19 PM ET
Korey Lee pinch-running for Andrew Benintendi.
4:19 PM ET
Andrew Benintendi walks. Miguel Vargas to second. Colson Montgomery to third. Chase Meidroth scores.
4:17 PM ET
Andrew Benintendi pinch-hitting for Curtis Mead.
4:17 PM ET
Edgar Quero strikes out swinging.
4:13 PM ET
Miguel Vargas walks. Colson Montgomery to second. Chase Meidroth to third. Dominic Fletcher scores.
4:10 PM ET
Mason Miller (P) replaces Kyle Hart (P).
4:09 PM ET
Colson Montgomery walks. Chase Meidroth to second. Dominic Fletcher to third.
4:07 PM ET
Kyle Teel strikes out swinging.
4:05 PM ET
Chase Meidroth walks.
4:03 PM ET
Dominic Fletcher doubles to shallow left field.
4:02 PM ET
Kyle Hart (P) replaces Adrian Morejon (P).
3:59 PM ET
Luis Arraez lines out to shortstop to Curtis Mead.
3:57 PM ET
Fernando Tatis singles to right field. Ryan O'Hearn to second.
3:56 PM ET
Elias Díaz lines out to deep left center field to Miguel Vargas.
3:55 PM ET
Jake Cronenworth pops out to shallow center field to Colson Montgomery.
3:53 PM ET
Ryan O'Hearn singles to left field.
3:52 PM ET
Michael A. Taylor remains in the game as CF.
3:52 PM ET
Curtis Mead remains in the game as 3B.
3:52 PM ET
Miguel Vargas switches from 3B to LF.
3:49 PM ET
Michael A. Taylor called out on strikes.
3:48 PM ET
Michael A. Taylor pinch-hitting for Will Robertson.
3:48 PM ET
Lenyn Sosa pops out to first base to Ryan O'Hearn.
3:46 PM ET
Curtis Mead strikes out on a foul tip.
3:44 PM ET
Curtis Mead pinch-hitting for Brooks Baldwin.
3:43 PM ET
Adrian Morejon (P) replaces Michael King (P).
3:41 PM ET
Edgar Quero walks. Miguel Vargas to second. Colson Montgomery to third.
3:38 PM ET
Miguel Vargas singles to right field. Colson Montgomery to second.
3:37 PM ET
Colson Montgomery singles to shallow center field.
3:34 PM ET
Gavin Sheets strikes out swinging.
3:31 PM ET
Ramón Laureano singles to right field, tagged out at second, Dominic Fletcher to Colson Montgomery.
3:30 PM ET
Jackson Merrill grounds out to shallow infield, Chase Meidroth to Lenyn Sosa.
3:27 PM ET
Kyle Teel strikes out swinging.
3:26 PM ET
Chase Meidroth grounds out to shallow infield, Manny Machado to Ryan O'Hearn.
3:25 PM ET
Dominic Fletcher flies out to center field to Jackson Merrill.
3:22 PM ET
Manny Machado flies out to right field to Dominic Fletcher.
3:21 PM ET
Luis Arraez walks.
3:19 PM ET
Fernando Tatis called out on strikes.
3:17 PM ET
Elias Díaz strikes out swinging.
3:15 PM ET
Mike Vasil (P) replaces Sean Burke (P).
3:13 PM ET
Will Robertson strikes out swinging.
3:12 PM ET
Lenyn Sosa flies out to left field to Ramón Laureano.
3:10 PM ET
Brooks Baldwin singles to right field.
3:08 PM ET
Edgar Quero grounds out to second base, Luis Arraez to Ryan O'Hearn.
3:06 PM ET
Jake Cronenworth grounds out to shallow infield to Lenyn Sosa.
3:04 PM ET
Ryan O'Hearn singles to center field.
3:03 PM ET
Gavin Sheets lines out to left field to Will Robertson.
3:01 PM ET
Ramón Laureano strikes out swinging.
2:58 PM ET
Miguel Vargas hits into a force out to shallow infield. Kyle Teel out at second.
2:57 PM ET
Colson Montgomery pops out to shortstop to Jake Cronenworth.
2:56 PM ET
Kyle Teel walks.
2:55 PM ET
Chase Meidroth grounds out to shortstop, Jake Cronenworth to Ryan O'Hearn.
2:51 PM ET
Jackson Merrill strikes out swinging.
2:49 PM ET
Manny Machado grounds out to shallow infield. Luis Arraez out at second.
2:48 PM ET
Luis Arraez singles to shallow center field.
2:47 PM ET
Fernando Tatis homers to left field.
2:44 PM ET
Dominic Fletcher flies out to right field to Fernando Tatis.
2:44 PM ET
Will Robertson flies out to shallow center field to Jake Cronenworth.
2:43 PM ET
Lenyn Sosa strikes out swinging.
2:41 PM ET
Brooks Baldwin walks. Edgar Quero to second.
2:39 PM ET
Edgar Quero singles to left center field.
2:36 PM ET
Elias Díaz flies out to left field to Will Robertson.
2:36 PM ET
Jake Cronenworth singles to shallow center field. Gavin Sheets scores.
2:34 PM ET
Ryan O'Hearn called out on strikes.
2:29 PM ET
Gavin Sheets singles to right field. Jackson Merrill to third.
2:27 PM ET
Ramón Laureano strikes out swinging.
2:27 PM ET
Ramón Laureano strikes out swinging.
2:25 PM ET
Jackson Merrill singles to deep right field.
2:21 PM ET
Miguel Vargas grounds out to third base. Kyle Teel out at second.
2:20 PM ET
Colson Montgomery called out on strikes.
2:18 PM ET
Kyle Teel walks. Chase Meidroth to second.
2:16 PM ET
Chase Meidroth hit by pitch.
2:14 PM ET
Manny Machado grounds out to shallow infield, Colson Montgomery to Lenyn Sosa.
2:13 PM ET
Luis Arraez flies out to shallow left field to Will Robertson.
2:11 PM ET
Fernando Tatis flies out to deep center field to Brooks Baldwin.

Chicago White Sox Team Statistics and Rankings

Win-Loss Record: 58-97
Home Record: 33-47
Away Record: 25-50
Division Record: 18-34
Streak: 1 Loss streak
Winning Percentage: .374

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San Diego Padres Team Statistics and Rankings

Win-Loss Record: 84-71
Home Record: 47-28
Away Record: 37-43
Division Record: 16-12
Streak: 1 Win streak
Winning Percentage: .542

Stat Leaders

Chicago White Sox (58-97, #5 in division)

Batting Average Leader: Corey Julks, 0.375
RBI Leader: Lenyn Sosa, 71 RBI
Home Run Leader: Lenyn Sosa, 21 HR
Runs Leader: Miguel Vargas, 73 Runs
Hits Leader: Lenyn Sosa, 129 Hits
Stolen Bases Leader: Luis Robert Jr., 33 SB
ERA Leader: Adrian Houser, 2.10 ERA
Strikeout Leader: Shane Smith, 129 K
Wins Leader: Davis Martin, 7 W
Saves Leader: Jordan Leasure, 7 SV

San Diego Padres (84-71, #2 in division)

Batting Average Leader: Bryce Johnson, 0.371
RBI Leader: Manny Machado, 93 RBI
Home Run Leader: Manny Machado, 26 HR
Runs Leader: Fernando Tatis Jr., 107 Runs
Hits Leader: Luis Arraez, 171 Hits
Stolen Bases Leader: Fernando Tatis Jr., 32 SB
ERA Leader: Mason Miller, 0.89 ERA
Strikeout Leader: Dylan Cease, 207 K
Wins Leader: Adrian Morejon, 13 W
Saves Leader: Robert Suarez, 39 SV

Chicago White Sox Injury Report

Luis Robert Jr. – Hamstring (D10) – The Chicago White Sox placed OF Luis Robert on the 10-day injured list with left hamstring strain.
Bryan Hudson – Back (D15) – The Chicago White Sox placed LHP Bryan Hudson on the 15-day injured list with a lower back strain.
Prelander Berroa – Elbow (D60) – The Chicago White Sox placed RHP Prelander Berroa on the 60-day injured list as he recovers from Tommy John surgery. He’s expected to miss the 2025 season.
Ky Bush – Elbow (D60) – The Chicago White Sox placed LHP Ky Bush on the 60-day injured list as he recovers from Tommy John surgery.
Martín Pérez – Shoulder (D15) – The Chicago White Sox placed LHP Martín Pérez on the 15-day injured list with a left shoulder strain.
Elvis Peguero – Elbow (D15) – The Chicago White Sox placed RHP Elvis Peguero on the 15-day injured list due to a right elbow strain.
Drew Thorpe – Elbow (D60) – The Chicago White Sox placed RHP Drew Thorpe on the 60-day injured list as he recovers from Tommy John surgery. He’s expected to miss the 2025 season.
Miguel Castro – Knee (D60) – The Chicago White Sox transferred RHP Miguel Castro to the 60-day injured list with a patellar tendon tear in his right knee.

San Diego Padres Injury Report

Nestor Cortes – Elbow (D15) – The San Diego Padres placed LHP Nestor Cortes on the 15-day injured list with left elbow tendinitis.
Jason Adam – Quad (D15) – The San Diego Padres placed RHP Jason Adam on the 15-day injured list with left quadriceps injury.
Joe Musgrove – Elbow (D60) – The San Diego Padres placed RHP Joe Musgrove on the 60-day injured list as he recovers from Tommy John surgery.
Jhony Brito – Forearm (D60) – The San Diego Padres transferred RHP Jhony Brito from the 15-day injured list to the 60-day injured list due to a forearm strain. Brito underwent a UCL and will miss the entire 2025 season.
Xander Bogaerts – Foot (D10) – The San Diego Padres placed INF Xander Bogaerts on the 10-day injured list with a non-displaced fracture in his left foot.
David Morgan – Shoulder (D15) – The San Diego Padres placed RHP David Morgan on the 15-day injured list with right shoulder inflammation.

Chicago White Sox Upcoming 2025 Schedule

September 21, 2025 vs San Diego Padres
September 23, 2025 at New York Yankees
September 24, 2025 at New York Yankees
September 25, 2025 at New York Yankees
September 26, 2025 at Washington Nationals
September 27, 2025 at Washington Nationals
September 28, 2025 at Washington Nationals

San Diego Padres Upcoming 2025 Schedule

September 21, 2025 at Chicago White Sox
September 22, 2025 vs Milwaukee Brewers
September 23, 2025 vs Milwaukee Brewers
September 24, 2025 vs Milwaukee Brewers
September 26, 2025 vs Arizona Diamondbacks
September 27, 2025 vs Arizona Diamondbacks
September 28, 2025 vs Arizona Diamondbacks

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