MLB

Seattle Mariners at Houston Astros – Where to Watch, Stream Info, TV Channel, and Live Updates (September 21, 2025)

September 21, 2025 by Fubo Sports Desk
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The Seattle Mariners, currently leading their division with an 86-69 record, are on a three-game winning streak as they face the Houston Astros, who sit at 84-71 and are experiencing a two-game losing streak. The Mariners have performed well on the road, holding a 38-42 away record, while the Astros boast a solid 46-34 home record. Key players for Seattle include Cal Raleigh, who leads the team with 119 RBIs and 57 home runs, and Andrés Muñoz, who has an impressive 1.49 ERA. For Houston, Jeremy Peña leads with a .304 batting average, and Hunter Brown has been a standout pitcher with 201 strikeouts this season. This matchup promises to be crucial as both teams vie for playoff positioning.

Seattle Mariners at Houston Astros Game Information

Game Date: September 21, 2025
Game Time: 07:10 PM ET
TV Channel: ESPN, ESPN Deportes
Location: Daikin Park, Houston, TX
Live Stream: Fubo (free trial)

Live Updates

10:02 PM ET
Jose Altuve called out on strikes.
10:00 PM ET
Victor Caratini flies out to center field to Julio Rodríguez.
9:58 PM ET
Victor Caratini pinch-hitting for Mauricio Dubón.
9:58 PM ET
Zach Cole grounds out to shallow right field, Josh Naylor to Matt Brash.
9:57 PM ET
Matt Brash (P) replaces Carlos Vargas (P).
9:57 PM ET
Mitch Garver remains in the game as DH.
9:55 PM ET
J.P. Crawford grounds out to shallow infield, Carlos Correa to Christian Walker.
9:53 PM ET
Victor Robles grounds out to shallow infield, Mauricio Dubón to Christian Walker.
9:52 PM ET
Mitch Garver flies out to shallow right field to Jose Altuve.
9:51 PM ET
Mitch Garver pinch-hitting for Dominic Canzone.
9:51 PM ET
Bryan King (P) replaces Nick Hernandez (P).
9:49 PM ET
Jake Meyers lines out to deep center field to Julio Rodríguez.
9:47 PM ET
Yainer Diaz reaches on error. Fielding error by J.P. Crawford.
9:46 PM ET
Christian Walker grounds out to shallow infield, Eugenio Suárez to Josh Naylor.
9:44 PM ET
Jesús Sánchez called out on strikes.
9:42 PM ET
Isaac Paredes homers to left field.
9:41 PM ET
Leo Rivas (2B) replaces Jorge Polanco (2B), batting 5th.
9:39 PM ET
Eugenio Suárez flies out to shallow center field to Zach Cole.
9:38 PM ET
Jorge Polanco flies out to center field to Jake Meyers. Josh Naylor to third.
9:33 PM ET
Josh Naylor doubles to second base.
9:30 PM ET
Julio Rodríguez strikes out on a foul tip.
9:28 PM ET
Nick Hernandez (P) replaces Craig Kimbrel (P).
9:26 PM ET
Carlos Correa grounds out to shallow infield. Jose Altuve out at second.
9:24 PM ET
Carlos Vargas (P) replaces Caleb Ferguson (P).
9:22 PM ET
Jose Altuve singles to shallow center field. Mauricio Dubón to third. Zach Cole scores.
9:19 PM ET
Mauricio Dubón singles to left field. Zach Cole to second.
9:18 PM ET
Zach Cole singles to shallow right field.
9:17 PM ET
Jake Meyers grounds out to shallow infield, Eugenio Suárez to Josh Naylor.
9:16 PM ET
Caleb Ferguson (P) replaces Logan Gilbert (P).
9:13 PM ET
Cal Raleigh strikes out swinging.
9:09 PM ET
Randy Arozarena called out on strikes.
9:06 PM ET
J.P. Crawford strikes out swinging.
9:05 PM ET
Craig Kimbrel (P) replaces AJ Blubaugh (P).
9:02 PM ET
Yainer Diaz grounds out to shortstop, J.P. Crawford to Josh Naylor.
8:58 PM ET
Christian Walker strikes out swinging.
8:56 PM ET
Jesús Sánchez lines out to left field to Randy Arozarena.
8:51 PM ET
Victor Robles flies out to deep center field to Jake Meyers.
8:50 PM ET
Dominic Canzone grounds out to shallow right field to Christian Walker.
8:48 PM ET
Eugenio Suárez flies out to right center field to Zach Cole.
8:44 PM ET
Isaac Paredes pops out to shallow infield to Eugenio Suárez.
8:39 PM ET
Carlos Correa flies out to left field to Randy Arozarena.
8:37 PM ET
Jose Altuve hit by pitch.
8:37 PM ET
Jose Altuve hit by pitch.
8:36 PM ET
Mauricio Dubón grounds out to shortstop, Eugenio Suárez to Josh Naylor.
8:32 PM ET
Jorge Polanco lines out to left center field to Jesús Sánchez.
8:31 PM ET
Josh Naylor lines out to left field to Jesús Sánchez.
8:29 PM ET
Julio Rodríguez grounds out to shallow infield, Carlos Correa to Christian Walker.
8:26 PM ET
Zach Cole flies out to center field to Julio Rodríguez.
8:25 PM ET
Jake Meyers flies out to deep right center field to Victor Robles.
8:23 PM ET
Yainer Diaz lines out to shallow left field to Eugenio Suárez.
8:21 PM ET
Christian Walker singles to deep center field.
8:18 PM ET
Cal Raleigh strikes out swinging.
8:16 PM ET
Randy Arozarena pops out to shallow right field to Christian Walker.
8:15 PM ET
J.P. Crawford grounds out to shortstop, Mauricio Dubón to Christian Walker.
8:13 PM ET
AJ Blubaugh (P) replaces Enyel De Los Santos (P).
8:11 PM ET
Jesús Sánchez flies out to center field to Julio Rodríguez.
8:09 PM ET
Isaac Paredes reaches on third strike. Jose Altuve to second.
8:06 PM ET
Carlos Correa called out on strikes.
8:02 PM ET
Jose Altuve walks.
7:58 PM ET
Mauricio Dubón strikes out swinging.
7:56 PM ET
Zach Cole homers to center field.
7:53 PM ET
Victor Robles called out on strikes.
7:51 PM ET
Dominic Canzone grounds out to second base. Eugenio Suárez out at second.
7:50 PM ET
Eugenio Suárez walks.
7:46 PM ET
Jake Meyers flies out to right field to Victor Robles.
7:45 PM ET
Yainer Diaz grounds out to shallow infield, Jorge Polanco to Josh Naylor.
7:44 PM ET
Christian Walker pops out to shallow infield to Josh Naylor.
7:40 PM ET
Jorge Polanco flies out to deep center field to Jake Meyers.
7:40 PM ET
Josh Naylor flies out to left center field to Jesús Sánchez.
7:39 PM ET
Enyel De Los Santos (P) replaces Jason Alexander (P).
7:37 PM ET
Julio Rodríguez singles to center field.
7:36 PM ET
Cal Raleigh homers to right field. Randy Arozarena scores.
7:34 PM ET
Randy Arozarena singles to shallow center field.
7:33 PM ET
J.P. Crawford homers to right field. Victor Robles scores. Dominic Canzone scores. Eugenio Suárez scores.
7:31 PM ET
Victor Robles walks. Dominic Canzone to second. Eugenio Suárez to third. Jorge Polanco scores.
7:29 PM ET
Dominic Canzone hits into a force out to shallow infield. Eugenio Suárez to second. Jorge Polanco to third. Josh Naylor out at home.
7:28 PM ET
Eugenio Suárez singles to deep right field. Jorge Polanco to second. Josh Naylor to third.
7:27 PM ET
Jorge Polanco singles to shallow infield. Josh Naylor to second.
7:25 PM ET
Josh Naylor singles to shallow infield.
7:22 PM ET
Jesús Sánchez grounds out to first base, Josh Naylor to Logan Gilbert.
7:20 PM ET
Isaac Paredes pops out to shallow infield to Josh Naylor.
7:20 PM ET
Carlos Correa grounds out to shortstop, J.P. Crawford to Josh Naylor.
7:18 PM ET
Jose Altuve doubles to left field.
7:15 PM ET
Julio Rodríguez grounds out to shallow infield, Mauricio Dubón to Christian Walker.
7:15 PM ET
Cal Raleigh strikes out swinging.
7:13 PM ET
Randy Arozarena grounds out to shortstop, Mauricio Dubón to Christian Walker.

Houston Astros Team Statistics and Rankings

Win-Loss Record: 84-71
Home Record: 46-34
Away Record: 38-37
Division Record: 15-15
Streak: 2 Loss streak
Winning Percentage: .542

Seattle Mariners Team Statistics and Rankings

Win-Loss Record: 86-69
Home Record: 48-27
Away Record: 38-42
Division Record: 21-11
Streak: 3 Win streak
Winning Percentage: .555

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Stat Leaders

Houston Astros (84-71, #2 in division)

Batting Average Leader: Jeremy Peña, 0.304
RBI Leader: Christian Walker, 82 RBI
Home Run Leader: Jose Altuve, 26 HR
Runs Leader: Jose Altuve, 78 Runs
Hits Leader: Jeremy Peña, 150 Hits
Stolen Bases Leader: Jeremy Peña, 20 SB
ERA Leader: Josh Hader, 2.05 ERA
Strikeout Leader: Hunter Brown, 201 K
Wins Leader: Hunter Brown, 12 W
Saves Leader: Josh Hader, 28 SV

Seattle Mariners (86-69, #1 in division)

Batting Average Leader: Dominic Canzone, 0.300
RBI Leader: Cal Raleigh, 119 RBI
Home Run Leader: Cal Raleigh, 57 HR
Runs Leader: Cal Raleigh, 106 Runs
Hits Leader: Julio Rodríguez, 170 Hits
Stolen Bases Leader: Randy Arozarena, 28 SB
ERA Leader: Andrés Muñoz, 1.49 ERA
Strikeout Leader: Bryan Woo, 198 K
Wins Leader: Bryan Woo, 15 W
Saves Leader: Andrés Muñoz, 37 SV

Houston Astros Injury Report

Zach Dezenzo – Hand (D60) – The Houston Astros placed INF Zach Dezenzo on the 60-day injured list with a left hand inflammation.
John Rooney – Concussion / Nasal (D60) – The Houston Astros transferred LHP John Rooney to the 60-day injured list with a left elbow inflammation.
Ronel Blanco – Elbow (D60) – The Houston Astros transferred RHP Ronel Blanco to the 60-day injured list with a right elbow inflammation.
Pedro León – Knee (D60) – The Houston Astros transferred OF Pedro León to the 60-day injured list due to a Grade 1 MCL strain.
Yordan Alvarez – Ankle (D10) – The Houston Astros placed OF Yordan Alvarez on the 10-day injured list with a left ankle sprain.
Kaleb Ort – Elbow (D60) – The Houston Astros placed RHP Kaleb Ort on the 60-day injured list due to right elbow inflammation.
Josh Hader – Shoulder (D15) – The Houston Astros placed LHP Josh Hader on the 15-day injured list due to a left shoulder strain.
Spencer Arrighetti – Elbow (D15) – The Houston Astros placed RHP Spencer Arrighetti on the 15-day injured list with right elbow inflammation.
Bennett Sousa – Elbow (D15) – The Houston Astros placed LHP Bennett Sousa on the 15-day injured list with left elbow inflammation.
Hayden Wesneski – Elbow (D60) – The Houston Astros transferred RHP Hayden Wesneski to the 60-day injured list from the 15-day injured list with right elbow inflammation.
Brandon Walter – Elbow (D60) – The Houston Astros transferred LHP Brandon Walter to the 60-day injured list with a left elbow inflammation.
Brendan Rodgers – Oblique (D60) – The Houston Astros placed INF Brendan Rodgers on the 60-day injured list with a left oblique strain.
Lance McCullers Jr. – Hand (D15) – The Houston Astros placed RHP Lance McCullers on the 15-day injured list with right hand soreness.
Luis Garcia – Elbow (D60) – The Houston Astros transferred RHP Luis Garcia to the 60-day injured list.

Seattle Mariners Injury Report

Trent Thornton – Achilles (D60) – The Seattle Mariners transferred RHP Trent Thornton to the 60-day injured list with a torn left achilles.
Ryan Bliss – Biceps (D60) – The Seattle Mariners transferred INF Ryan Bliss to the 60-day injured list with a left biceps tear.
Bryan Woo – Pectoral (Day-to-Day) – Woo left Friday’s (Sep. 19) game with a Pectoral tightness.
Gregory Santos – Knee (D60) – The Seattle Mariners placed RHP Gregory Santos on the 60-day injured list as he deals with right knee inflammation.
Jackson Kowar – Shoulder (D15) – The Seattle Mariners placed RHP Jackson Kowar on the 15-day injured list with a right shoulder impingement.
Logan Evans – Elbow (D15) – The Seattle Mariners placed RHP Logan Evans on the 15-day injured list with right elbow inflammation.

Houston Astros Upcoming 2025 Schedule

September 21, 2025 vs Seattle Mariners
September 23, 2025 at Athletics
September 24, 2025 at Athletics
September 25, 2025 at Athletics
September 26, 2025 at Los Angeles Angels
September 27, 2025 at Los Angeles Angels
September 28, 2025 at Los Angeles Angels

Seattle Mariners Upcoming 2025 Schedule

September 21, 2025 at Houston Astros
September 23, 2025 vs Colorado Rockies
September 24, 2025 vs Colorado Rockies
September 25, 2025 vs Colorado Rockies
September 26, 2025 vs Los Angeles Dodgers
September 27, 2025 vs Los Angeles Dodgers
September 28, 2025 vs Los Angeles Dodgers

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