Arizona Cardinals at Indianapolis Colts – Where to Watch, Stream Info, TV Channel, and Live Updates (October 12, 2025)

The Arizona Cardinals will face off against the Indianapolis Colts in a matchup featuring contrasting fortunes. The Cardinals enter the game with a record of 2-3, having lost their last three contests. Their offense has averaged 288.4 yards per game, with quarterback Kyler Murray leading the team with 962 passing yards and six touchdowns. In contrast, the Colts boast a strong 4-1 record, currently sitting atop their conference and division. They have been particularly effective at home, winning all three of their home games this season. The Colts’ offense averages 381.2 yards per game and has scored an impressive 32.6 points per game, led by quarterback Daniel Jones. This game presents a critical opportunity for both teams to either halt a losing streak or maintain momentum.

Arizona Cardinals at Indianapolis Colts Game Information

Game Date: October 12, 2025
Game Time: 01:00 PM ET
TV Channel: FOX
Location: Lucas Oil Stadium, Indianapolis, IN
Live Stream: Fubo (free trial)

Indianapolis Colts Team Statistics and Rankings

Win-Loss Record: 4-1
Rankings: #1 in Conference, #1 in Division
Home/Away Records: 3-0 at home
Conference Record: 4-0
Division Record: 1-0
Streak: Won 1

Indianapolis Colts Offensive Statistics

Total Offense: 1906 yards (Avg. 381.2 yards per game)
Passing Offense: 1265 yards (Avg. 253.0 yards per game)
Rushing Offense: 641 yards (Avg. 128.2 yards per game)
Points Scored: 163 points (Avg. 32.6 points per game)
Efficiency Stats: Red Zone: 60.0% (15/25) | Third Down: 46.6% (27/58)

Indianapolis Colts Defensive Statistics

Total Defense: 1575 yards (Avg. 315.0 yards per game)
Passing Defense: 1085 yards (Avg. 217.0 yards per game)
Rushing Defense: 490 yards (Avg. 98.0 yards per game)
Points Allowed: 89 points (Avg. 17.8 points per game)
Advanced Defensive Stats: Fourth Down Stops: 4 | Three & Outs Forced: 5 | QB Hurries: 10 | Batted Passes: 5

Indianapolis Colts Individual Stat Leaders

Passing: Daniel Jones, 107 Completions/150 Attempts (71.3%), 1290 Yards, 6 Touchdowns, 2 Interceptions
Rushing: Jonathan Taylor, 94 Attempts, 480 Yards (5.1 avg), 6 Touchdowns
Receiving: Tyler Warren, 23 Receptions, 307 Yards, 1 Touchdowns
Tackles: Nick Cross, 43 Tackles (23 solo, 20 assists)
Sacks: Tyquan Lewis, 3 Sacks
Interceptions: Cam Bynum, 2 Interceptions

Arizona Cardinals Team Statistics and Rankings

Win-Loss Record: 2-3
Rankings: #13 in Conference, #4 in Division
Home/Away Records: 1-2 at home
Conference Record: 2-2
Division Record: 0-2
Streak: Lost 3

Arizona Cardinals Offensive Statistics

Total Offense: 1442 yards (Avg. 288.4 yards per game)
Passing Offense: 851 yards (Avg. 170.2 yards per game)
Rushing Offense: 591 yards (Avg. 118.2 yards per game)
Points Scored: 103 points (Avg. 20.6 points per game)
Efficiency Stats: Red Zone: 58.8% (10/17) | Third Down: 39.7% (27/68)

Arizona Cardinals Defensive Statistics

Total Defense: 1733 yards (Avg. 346.6 yards per game)
Passing Defense: 1271 yards (Avg. 254.2 yards per game)
Rushing Defense: 462 yards (Avg. 92.4 yards per game)
Points Allowed: 96 points (Avg. 19.2 points per game)
Advanced Defensive Stats: Fourth Down Stops: 5 | Three & Outs Forced: 9 | QB Hurries: 10 | Batted Passes: 4

Arizona Cardinals Individual Stat Leaders

Passing: Kyler Murray, 110 Completions/161 Attempts (68.3%), 962 Yards, 6 Touchdowns, 3 Interceptions
Rushing: Kyler Murray, 29 Attempts, 173 Yards (6.0 avg), 1 Touchdowns
Receiving: Marvin Harrison Jr., 20 Receptions, 306 Yards, 2 Touchdowns
Tackles: Mack Wilson Sr., 41 Tackles (22 solo, 19 assists)
Sacks: Josh Sweat, 5 Sacks
Interceptions: Dadrion Taylor-Demerson, 2 Interceptions

Indianapolis Colts Injury Report

Charvarius Ward – NIR – Rest (Did Not Participate In Practice)
Tyler Goodson – Groin (Did Not Participate In Practice)
Tyquan Lewis – Illness (Full Participation In Practice)
Kenny Moore II – Achilles (Did Not Participate In Practice)
Alec Pierce – Concussion (Full Participation In Practice)
Braden Smith – Rest (Full Participation In Practice)
Grover Stewart – Biceps (Full Participation In Practice)
DeForest Buckner – NIR – Rest (Did Not Participate In Practice)
Samson Ebukam – NIR – Rest (Limited Participation In Practice)

Arizona Cardinals Injury Report

Darius Robinson – Pectoral (Did Not Participate In Practice)
Kyler Murray – Foot (Limited Participation In Practice)
Kelvin Beachum – Rest (Full Participation In Practice)
Evan Brown – Hamstring (Full Participation In Practice)
Will Hernandez – Knee (Full Participation In Practice)
Zay Jones – Knee (Limited Participation In Practice)
Max Melton – Hamstring (Limited Participation In Practice)
Cody Simon – Knee (Limited Participation In Practice)
Jonah Williams – Foot (Full Participation In Practice)
Mack Wilson Sr. – Ankle (Limited Participation In Practice)
Calais Campbell – NIR – Rest (Did Not Participate In Practice)
Will Johnson – Groin (Full Participation In Practice)
Blake Gillikin – Back (Did Not Participate In Practice)

Indianapolis Colts Upcoming 2025 Schedule

October 19, 2025 at Los Angeles Chargers
October 26, 2025 vs Tennessee Titans
November 02, 2025 at Pittsburgh Steelers
November 09, 2025 vs Atlanta Falcons
November 23, 2025 at Kansas City Chiefs
November 30, 2025 vs Houston Texans
December 07, 2025 at Jacksonville Jaguars
December 14, 2025 at Seattle Seahawks
December 22, 2025 vs San Francisco 49ers
December 28, 2025 vs Jacksonville Jaguars

Arizona Cardinals Upcoming 2025 Schedule

October 19, 2025 vs Green Bay Packers
November 03, 2025 at Dallas Cowboys
November 09, 2025 at Seattle Seahawks
November 16, 2025 vs San Francisco 49ers
November 23, 2025 vs Jacksonville Jaguars
November 30, 2025 at Tampa Bay Buccaneers
December 07, 2025 vs Los Angeles Rams
December 14, 2025 at Houston Texans
December 21, 2025 vs Atlanta Falcons
December 28, 2025 at Cincinnati Bengals