How to Watch Panthers vs 49ers: Stream NFL Week 12 Live, TV Channel

Bryce Young and the Carolina Panthers will face off against Brock Purdy and the San Francisco 49ers in Week 12 of the NFL season.

The Carolina Panthers will head on the road for their Week 12 game against the San Francisco 49ers in an NFC showdown at Levi’s Stadium in San Francisco, California, on Monday Night Football. The Panthers have clawed back into the NFC playoff mix, sitting at 6–5 this season and battling for positioning in a tightly contested NFC South race. Recently, this team has been on a roller coaster, with statement wins over the Atlanta Falcons, Green Bay Packers, Dallas Cowboys, and New York Jets offset by tough losses to the Buffalo Bills and New Orleans Saints.

How to Watch Carolina Panthers vs San Francisco 49ers Today:

Game Date: Monday, Nov. 24, 2025

Game Time: 8:00 p.m. ET

TV Channel: ESPN, ESPN Deportes, ESPN2

Location: Levi’s Stadium

Live stream Carolina Panthers vs San Francisco 49ers on Fubo: Start Watching Today!

A 6–4 mark over their last 10 contests underscores a group learning how to close out games. Carolina is led by a quarterback learning himself in Bryce Young, who has thrown for 1,962 yards and 14 touchdowns, including several comeback victories. The emergence of Rico Dowdle has been the catalyst for this offense. He has 168 attempts for 833 yards and five touchdowns in just a few games.

The 49ers are continuing a strong season with a 9-2 record, leading the NFC West and positioning themselves as a top playoff contender. In the last few weeks, they picked up a big win, dominating 41-22 victory over the Arizona Cardinals featuring standout performances from Brock Purdy, who threw for 200 yards and three touchdowns, and Christian McCaffrey, who combined for three total touchdowns on both the ground and through the air with 121 all-purpose yards.

The was a jolt of life after San Francisco suffered a crucial defeat at the hands of the NFC-leading Los Angeles Rams, 42-26. Purdy, who was not back from injury at the time, was replaced by Mac Jones, who had 319 yards and three touchdowns. San Francisco just didn’t have a defensive answer to what LA was doing on offense, despite Tatum Bethune having 10 tackles.

What Time Is The NFL Game Between Carolina vs San Francisco On?

The Carolina Panthers vs San Francisco 49ers game will take place on Monday, Nov. 24, 2025 at 8:00 p.m. ET. Tune in and catch some great National Football League action.

What Channel Is The Carolina Panthers vs San Francisco 49ers Game On?

Looking to watch this game? Fans can tune into ESPN, ESPN Deportes, ESPN2 to see the action. Make sure you subscribe to Fubo now to watch this game and many other football games.

Live stream Carolina Panthers vs San Francisco 49ers on Fubo: Start Watching Today!

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