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When three high-schoolers are gunned down in their car, police launch an investigation into why they came to such a violent end; ten years later, that investigation reaches a dramatic conclusion in an Albuquerque courtroom.

Girly Chew had been worried about her safety; the investigation into her disappearance would take police into a world of aliens and reptiles, cancer cures and cannibalism, a world inhabited by a charismatic conman and his extra-terrestrial soul-mate.

Terri Gilbert said she didn't know who was coming down the basement steps; she shot and killed him; turned out to be her husband whom she was divorcing; twenty years earlier, she told a similar story, about her first husband.

The jury listened to detailed testimony about evidence recovered from the snowy crime scene where John O'Keefe was found. Prosecutors wanted to deliver enough clues for jurors to prove the allegation that the defendant used her SUV to kill her boyfriend. The cross-examination of forensic scientist, Ashley Vallier, who examined key pieces of evidence in her crime lab, began. The Defense wanted to show the jury that the crime scene was manipulated hours before evidence was collected.

Trace evidence was key for the prosecution as it tried to link Karen Read to the murder of her boyfriend, John O'Keefe. So, the State brought in yet another forensic scientist. This portion of the trial was all about the physical evidence inspected by forensic analysts. What was retrieved from the snowy crime scene after O'Keefe died, was then brought back to the State's lab and examined.

Jurors heard more details about the physical evidence found in the area where John O'Keefe was discovered. For a third time in a row, the State brought in a forensic scientist from the Massachusetts State Crime Lab to tell the jury about test results. Crime scene analysts looked for a physical match when examining the evidence in the case against Karen Read. Prosecutors argued that this evidence linked her to the death of her boyfriend in a hit-and-run.

A sergeant from the Massachusetts State Police took the stand. Yuriy Bukhenik was the supervisor of the lead detective in the investigation into the death of John O'Keefe. When Massachusetts State Police took over this case, the first thing they did was interview the defendant and impound her SUV. The state police took over this case due to a conflict of interest involving a Canton police officer.

Jurors saw the physical evidence collected by investigators. It included the clothing and sneakers John O'Keefe was wearing the night before he was found in a pile of snow. Next, the jury heard about the first formal interview the state police did with the defendant just hours after O'Keefe died. According to the sergeant on the stand, investigators drove to Karen Read's family home to ask her specific questions about the hours leading up to John's death.