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House treats a young married couple with similar symptoms, but they are shocked by the cause of the illness; a walk-in patient, David Morse, stands up to House.
After being found in a coma at his apartment, a 600-pound man is admitted to the hospital; House spends the night in jail after being arrested for a number of violations.
When the son of a man in a vegetative state starts going into a coma, the vegetative man is reawakened chemically by House, who hopes to get some clues to the son's problems.
House challenges his co-workers to correctly diagnose the ailment of an 18-year-old heart-attack patient, Patrick Fugit.
House takes the divorced parents of a young patient to court when their bickering prevents a decision on her treatment.
House is furious about Wilson striking a deal with Tritter; he tries to diagnose a little person's serious illness.
Trent (Jimmy Wlcek) is stabbed by an assassin (guest star Gary Busey) as he escorts a Special Olympics athlete (guest star Andrea Fay Friedman) to running practice. With Chuck Norris.
Walker and Trivette (Chuck Norris, Clarence Gilyard) go undercover at a school to prove that a principal's death was not a suicide. Guest star: James Remar.