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Boston College at Syracuse
NCAAFThe Orange (3-8, 1-6 ACC) and Eagles (1-10, 0-7) close out the 2025 campaign with this tilt. Boston College has won two straight meetings, and four of its last five visits to Syracuse. The programs have lost a combined 17 consecutive outings.
Duke at Tulane
NCAAFThe Green Wave (2-0) attempt to remain undefeated when they host the Blue Devils (1-1). Duke has won three straight meetings, the last in 2015, to lead the series against Tulane 3-2. Darian Mensah (DUKE) has thrown for 723 yards and five TDs in 2025.
Pittsburgh at Georgia Tech
NCAAFThe Panthers line up against the No. 16 Yellow Jackets. Georgia Tech bounced back from its first loss of the season by outlasting Boston College, 36-34 on Nov. 15. Pittsburgh had a five-game win streak snapped in a loss to then-No. 9 Notre Dame.
Florida State at Florida
NCAAFThe Seminoles (5-6) try to clinch bowl eligibility as they visit the Gators (3-8) in a Florida Cup clash. Florida won four of the last six Sunshine Showdown meetings, but Florida State picked up a 24-15 victory in its last visit to The Swamp in 2023.
SMU at Clemson
NCAAFThe Mustangs (4-2, 2-0 ACC) visit the Tigers (3-3, 2-2). Clemson earned a record 22nd ACC title by beating SMU 34-31 on a buzzer-beating field goal Dec. 7, 2024. Bryant Wesco Jr. (CLEM) is among the nation's leaders with 537 receiving yards in 2025.
Miami at SMU
NCAAFThe No. 10 Hurricanes (6-1, 2-1) head to Big D for an ACC affair with the Mustangs (5-3, 3-1). SMU won the only prior meeting, 7-3 in 1965. Miami bounced back from a stunning setback against Louisville with a 42-7 victory over Stanford last week.
Virginia at NC State
NCAAFThe Cavaliers clash with the Wolfpack in this ACC opener. Virginia put the boots to Coastal Carolina 48-7 in Week 1, while NC State defeated in-state rival East Carolina 24-17. The Wolfpack clipped the Cavs 24-21 during the last get-together in 2023.
California at Stanford
NCAAFThe Cardinal host the Golden Bears. Stanford leads the all-time series 65-51-11, but California has won four straight meetings after rallying to keep the streak alive in 2024. Cal stunned then-No. 15 Louisville in overtime prior to its bye Nov. 8.
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Duke at Clemson
NCAAFThe Tigers (3-4, 2-3 ACC) and Blue Devils (4-3, 3-1) return from the bye. In 2023, Duke snapped a five-game series slide with its first victory over Clemson since 2004. Duke's three-game win streak was snapped by undefeated Georgia Tech on Oct. 18.
#10 Miami vs #2 Ohio State
NCAAFThe No. 10 Miami Hurricanes face the No. 2 Ohio State Buckeyes at AT&T Stadium. This is a high-stakes College Football Playoff Quarterfinal matchup. Miami advanced after a gritty 10-3 road upset over No. 7 Texas A&M in the CFP First Round.
#10 Miami vs #6 Ole Miss
NCAAFNo. 6 Ole Miss faces No. 10 Miami in the Fiesta Bowl at State Farm Stadium for a spot in the College Football Playoff semifinals. The Rebels seek an eighth straight win behind Kewan Lacy (23 TDs), while the Hurricanes lean on QB Carson Beck (27 TDs).
Clemson at Georgia Tech
NCAAFThe No. 12 Tigers seek a 10th straight win over the Yellow Jackets in this match from Bobby Dodd Stadium. Clemson doubled up Georgia Tech 42-21 behind four TD passes from Cade Klubnik on Nov. 11, 2023. Georgia Tech leads the all-time series 51-36-2.
#10 Miami at #7 Texas A&M
NCAAFThe No. 7 Aggies host the No. 10 Hurricanes in the College Football Playoff's first round. Texas A&M saw its undefeated season, and its chance at the SEC title, spoiled in a Nov. 28 loss at Texas. These programs traded home wins in 2022 and 2023.
Louisville at Miami
NCAAFThe Cardinals (4-1, 1-1 ACC) try to bounce back against a tough foe in the No. 2 Hurricanes (5-0, 1-0). Louisville dropped its first game of the season in a 30-27 overtime decision versus Virginia on Oct. 4. Miami defeated Louisville 52-45 last year.