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North Texas at 5 Indiana
NCAAFThe Mean Green play the Hoosiers at Memorial Stadium in Bloomington for a Saturday Week 1 opener. Indiana enters after finishing No. 1 in the final 2025 poll, while North Texas looks to improve upon a No. 24 rank finish from the previous year.
Boise State at 6 Oregon
NCAAFThe Boise State Broncos meet the Oregon Ducks at Autzen Stadium for an NCAA football game. Boise State ended their 2025 season with a 38-10 loss against Washington, while Oregon broke an eight-game win streak with a 56-22 loss against Indiana.
Fresno State at 14 USC
NCAAFThe USC Trojans host the Fresno State Bulldogs in Los Angeles for a Week 1 game. Home USC looks to build on a 42-26 victory over the Spartans led by quarterback Jayden Maiava, while visiting Fresno State looks to build on an 18-3 last season win.
Ohio at Nebraska
NCAAFThe Nebraska Cornhuskers host the Ohio Bobcats at Memorial Stadium in Lincoln. Nebraska opens its 2026 campaign after concluding last fall with a 44-22 bowl loss to Utah, while Ohio begins the year following a 9-4 overall record in 2025.
Marshall at 16 Penn State
NCAAFThe Marshall Thundering Herd face the Penn State Nittany Lions at Beaver Stadium. Marshall lost their final game of the 2025 season against Georgia Southern 24-19. Penn State had a four-game win streak, including a 22-10 win against Clemson.
Toledo at Michigan State
NCAAFToledo Rockets visit the Michigan State Spartans at Spartan Stadium to open the season. The home Spartans look to improve on a 4-8 finish in 2025, while the visiting Rockets targets early momentum coming off an 8-5 record last season.
Wisconsin at 3 Notre Dame
NCAAFNotre Dame plays host to Wisconsin at Lambeau Field in Green Bay to open the 2026 season. The Fighting Irish look to build on their 10-2 finish from last season, while the Badgers look to bounce back from their 17-7 loss to the Golden Gophers.
Rutgers at Boston College
NCAAFThe Eagles host the Scarlet Knights at Alumni Stadium in Chestnut Hill. Rutgers enters Week 2 following a 37-21 loss to the Massachusetts Minutemen, while Boston College seeks recovery after falling 34-15 to the Cincinnati Bearcats in Week 1.
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Marshall at 16 Penn State
NCAAFThe Marshall Thundering Herd face the Penn State Nittany Lions at Beaver Stadium. Marshall lost their final game of the 2025 season against Georgia Southern 24-19. Penn State had a four-game win streak, including a 22-10 win against Clemson.
Northern Illinois at 21 Iowa
NCAAFThe Iowa Hawkeyes host the Northern Illinois Huskies at Kinnick Stadium for Week 1. Known for defensive discipline, the Hawkeyes look to control the line of scrimmage, while a physical, run-heavy Huskies squad arrives to disrupt the tempo.
Hampton at Maryland
NCAAFThe Hampton Pirates play the Maryland Terrapins at SECU Stadium to open the 2026 season. Big Ten host Maryland showcases its explosive passing offense at home, welcoming regional FCS foe Hampton for a season-opening non-conference football game.
South Dakota State at Northwestern
NCAAFThe South Dakota State Jackrabbits visit the Northwestern Wildcats at Martin Stadium. South Dakota State opened its season with a 70-7 victory over Stetson as James Basinger rushed for 110 yards. Northwestern begins its 2026 season at home.
North Texas at 5 Indiana
NCAAFThe Mean Green play the Hoosiers at Memorial Stadium in Bloomington for a Saturday Week 1 opener. Indiana enters after finishing No. 1 in the final 2025 poll, while North Texas looks to improve upon a No. 24 rank finish from the previous year.
Western Michigan at Michigan
NCAAFThe Michigan Wolverines host the Western Michigan Broncos at Michigan Stadium as both teams open the 2026 season. Michigan opens its season at the Big House, welcoming in-state opponent Western Michigan to Ann Arbor for a non-conference game.
Washington State at 19 Washington
NCAAFWashington hosts Washington State at Husky Stadium for the annual Apple Cup showcase. Both teams look to build early momentum as they open Week 1. UW looks to build on a 9-4 campaign with the LA Bowl win, while WSU targets a tough road turnaround.
UCLA at California
NCAAFThe UCLA Bruins face the California Golden Bears at California Memorial Stadium in Berkeley. The Bruins ended their 2025 season with a five-game losing streak, while the Golden Bears lost against the Rainbow Warriors 35-31 in December 2025.