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Tennessee Titans at San Francisco 49ers

The 49ers emerge from their bye and host the Titans. San Francisco has won three in a row. Tennessee snapped a seven-game slide with a 31-29 decision at Cleveland in Week 14. Tony Pollard (TEN) turned 25 carries into 161 yards and two TDs in the win.

Live and upcoming for San Francisco 49ers

Tue Dec 23, 1:00am UTC • 3h 15m • ABC

San Francisco 49ers at Indianapolis Colts

NFL

The Colts host the 49ers in clash of playoff contenders. Indianapolis won the last five meetings, last losing to San Francisco 40-21 in 2001. Peyton Manning (IND) was 31-of-51 for 370 yards with a touchdown and four interceptions in that game.

Tue Dec 23, 1:00am UTC • 3h 15m • ESPN Deportes

San Francisco 49ers at Indianapolis Colts

NFL

Semana 16 de la temporada regular 2025 de la NFL. Los Colts mantienen una marca de 6-1 en el Lucas Oil Stadium, mientras que los 49ers registran 6-2 como visitantes. Ambos equipos necesitan acumular victorias para asegurar el pase de comodín.

Schedule

Date	Away	Home	Time
Sun, Dec 14	Washington Commanders	New York Giants	6:00 PM UTC
Sun, Dec 14	Las Vegas Raiders	Philadelphia Eagles	6:00 PM UTC
Sun, Dec 14	Cleveland Browns	Chicago Bears	6:00 PM UTC
Sun, Dec 14	Baltimore Ravens	Cincinnati Bengals	6:00 PM UTC
Sun, Dec 14	Arizona Cardinals	Houston Texans	6:00 PM UTC
Sun, Dec 14	Buffalo Bills	New England Patriots	6:00 PM UTC
Sun, Dec 14	New York Jets	Jacksonville Jaguars	6:00 PM UTC
Sun, Dec 14	Los Angeles Chargers	Kansas City Chiefs	6:00 PM UTC
Sun, Dec 14	Indianapolis Colts	Seattle Seahawks	9:25 PM UTC
Sun, Dec 14	Tennessee Titans	San Francisco 49ers	9:25 PM UTC
Sun, Dec 14	Green Bay Packers	Denver Broncos	9:25 PM UTC
Sun, Dec 14	Carolina Panthers	New Orleans Saints	9:25 PM UTC
Sun, Dec 14	Detroit Lions	Los Angeles Rams	9:25 PM UTC
Mon, Dec 15	Minnesota Vikings	Dallas Cowboys	1:20 AM UTC
Tue, Dec 16	Miami Dolphins	Pittsburgh Steelers	1:15 AM UTC
Fri, Dec 19	Los Angeles Rams	Seattle Seahawks	1:15 AM UTC
Sat, Dec 20	Philadelphia Eagles	Washington Commanders	10:00 PM UTC
Sun, Dec 21	Green Bay Packers	Chicago Bears	1:20 AM UTC
Sun, Dec 21	Buffalo Bills	Cleveland Browns	6:00 PM UTC
Sun, Dec 21	Cincinnati Bengals	Miami Dolphins	6:00 PM UTC
Sun, Dec 21	Los Angeles Chargers	Dallas Cowboys	6:00 PM UTC
Sun, Dec 21	New York Jets	New Orleans Saints	6:00 PM UTC
Sun, Dec 21	Tampa Bay Buccaneers	Carolina Panthers	6:00 PM UTC
Sun, Dec 21	Minnesota Vikings	New York Giants	6:00 PM UTC
Sun, Dec 21	Kansas City Chiefs	Tennessee Titans	6:00 PM UTC
Sun, Dec 21	Jacksonville Jaguars	Denver Broncos	9:05 PM UTC
Sun, Dec 21	Atlanta Falcons	Arizona Cardinals	9:05 PM UTC
Sun, Dec 21	Las Vegas Raiders	Houston Texans	9:25 PM UTC
Sun, Dec 21	Pittsburgh Steelers	Detroit Lions	9:25 PM UTC
Mon, Dec 22	New England Patriots	Baltimore Ravens	1:20 AM UTC