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Tennessee Titans at San Francisco 49ers

The 49ers emerge from their bye and host the Titans. San Francisco has won three in a row. Tennessee snapped a seven-game slide with a 31-29 decision at Cleveland in Week 14. Tony Pollard (TEN) turned 25 carries into 161 yards and two TDs in the win.

Live and upcoming for San Francisco 49ers

Tue Dec 23, 1:00am UTC • 3h 15m • ABC

San Francisco 49ers at Indianapolis Colts

NFL

The Colts host the 49ers in clash of playoff contenders. Indianapolis won the last five meetings, last losing to San Francisco 40-21 in 2001. Peyton Manning (IND) was 31-of-51 for 370 yards with a touchdown and four interceptions in that game.

Tue Dec 23, 1:00am UTC • 3h 15m • ESPN Deportes

San Francisco 49ers at Indianapolis Colts

NFL

Semana 16 de la temporada regular 2025 de la NFL. Los Colts mantienen una marca de 6-1 en el Lucas Oil Stadium, mientras que los 49ers registran 6-2 como visitantes. Ambos equipos necesitan acumular victorias para asegurar el pase de comodín.

Schedule

Date	Away	Home	Time
Tue, Dec 16	Miami Dolphins	Pittsburgh Steelers	1:15 AM UTC
Fri, Dec 19	Los Angeles Rams	Seattle Seahawks	1:15 AM UTC
Sat, Dec 20	Philadelphia Eagles	Washington Commanders	10:00 PM UTC
Sun, Dec 21	Green Bay Packers	Chicago Bears	1:20 AM UTC
Sun, Dec 21	Buffalo Bills	Cleveland Browns	6:00 PM UTC
Sun, Dec 21	Cincinnati Bengals	Miami Dolphins	6:00 PM UTC
Sun, Dec 21	Los Angeles Chargers	Dallas Cowboys	6:00 PM UTC
Sun, Dec 21	New York Jets	New Orleans Saints	6:00 PM UTC
Sun, Dec 21	Tampa Bay Buccaneers	Carolina Panthers	6:00 PM UTC
Sun, Dec 21	Minnesota Vikings	New York Giants	6:00 PM UTC
Sun, Dec 21	Kansas City Chiefs	Tennessee Titans	6:00 PM UTC
Sun, Dec 21	Jacksonville Jaguars	Denver Broncos	9:05 PM UTC
Sun, Dec 21	Atlanta Falcons	Arizona Cardinals	9:05 PM UTC
Sun, Dec 21	Las Vegas Raiders	Houston Texans	9:25 PM UTC
Sun, Dec 21	Pittsburgh Steelers	Detroit Lions	9:25 PM UTC
Mon, Dec 22	New England Patriots	Baltimore Ravens	1:20 AM UTC
Tue, Dec 23	San Francisco 49ers	Indianapolis Colts	1:15 AM UTC
Thu, Dec 25	Dallas Cowboys	Washington Commanders	6:00 PM UTC
Thu, Dec 25	Detroit Lions	Minnesota Vikings	9:30 PM UTC
Fri, Dec 26	Denver Broncos	Kansas City Chiefs	1:15 AM UTC
Sat, Dec 27	Houston Texans	Los Angeles Chargers	9:30 PM UTC
Sun, Dec 28	Baltimore Ravens	Green Bay Packers	1:00 AM UTC
Sun, Dec 28	Tampa Bay Buccaneers	Miami Dolphins	6:00 PM UTC
Sun, Dec 28	New England Patriots	New York Jets	6:00 PM UTC
Sun, Dec 28	Pittsburgh Steelers	Cleveland Browns	6:00 PM UTC
Sun, Dec 28	Arizona Cardinals	Cincinnati Bengals	6:00 PM UTC
Sun, Dec 28	New Orleans Saints	Tennessee Titans	6:00 PM UTC
Sun, Dec 28	Jacksonville Jaguars	Indianapolis Colts	6:00 PM UTC
Sun, Dec 28	Seattle Seahawks	Carolina Panthers	6:00 PM UTC
Sun, Dec 28	New York Giants	Las Vegas Raiders	9:05 PM UTC