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When you're young and single in the city, your friends are your family. A tight-knit group of friends living in Manhattan -- three girls and three guys -- navigate the complexities of adulthood and rely on the companionship, comfort and support they get from each other to deal with the pressures of life.

When you're young and single in the city, your friends are your family. A tight-knit group of friends living in Manhattan -- three girls and three guys -- navigate the complexities of adulthood and rely on the companionship, comfort and support they get from each other to deal with the pressures of life.

Against Alan's judgment, Charlie falls for a seemingly crazy woman named Frankie. Guest star: Jenna Elfman.

Charlie must face his feelings when Rose announces she is moving to London; Alan fudges his online dating profile, only to wind up with a fellow profile-embellisher.

Dan is finally ready to share his feelings with Louise; Darlene realizes how badly she wants a baby; Ben gets caught up playing handyman and babysitter for Becky, which causes him to miss an important meeting.

Dan and Louise take their relationship to the next level and come to appreciate the complexities of aging; Darlene spends the night in jail and leaves parenting duties to Ben; Mark and a friend's class experiment leaves them both with hickeys.

Eve surprises Mike and Vanessa with her decision about college; Kyle and Mandy decide to have Ed's recently deceased dog stuffed.

The winner of the "Meet Outdoor Man" contest thinks Mike's video log contains secret messages; Vanessa starts a lending library to meet people in her neighborhood; Chuck adjusts to his new life after his wife takes a job in Los Angeles.