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After being brought back from the dead as a genetically enhanced warrior, Luc Deveraux (Jean-Claude Van Damme) is now fully human and working with scientist Dylan Cotner (Xander Berkeley) to create a new, safer breed of fighters. When Cotner's project loses its funding, his supercomputer, the sentient SETH (Michael Jai White), is scheduled to be turned off. Alarmed, SETH takes over a human body to defend itself. To prevent the machine from destroying mankind, Luc must fight back.
After being brought back from the dead as a genetically enhanced warrior, Luc Deveraux (Jean-Claude Van Damme) is now fully human and working with scientist Dylan Cotner (Xander Berkeley) to create a new, safer breed of fighters. When Cotner's project loses its funding, his supercomputer, the sentient SETH (Michael Jai White), is scheduled to be turned off. Alarmed, SETH takes over a human body to defend itself. To prevent the machine from destroying mankind, Luc must fight back.