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Growing up in racially segregated Birmingham, Alabama, during the 1960's, Rene and Mary Elizabeth manage to stick together despite community intolerance of "mixed" friendships. Many years later, following the death of her father, Rene returns home and reunites with Mary Elizabeth. The women realize that despite their career and family differences, they can help each other find happiness.
S2, EP19 "You Pay Your Dues"
M.E deals with a burglary; the Bar Association files charges against Lakeisha; young M.E. and Rene gamble.
S2, EP20 "You Think I Am Lying to You?"
Mary Elizabeth (Annie Potts) and her family deal with the fact that one of their neighbors might be a pedophile.
S2, EP21 "The Toolshed Behind the Church"
Rene represents Bill regarding his involvement in a controversial shooting; Mary Elizabeth finishes her book.
S2, EP22 "Who Abandoned Who?"
Rene and Mary Elizabeth attend their high-school reunion, reminiscing about their school's integration.
S2, EP18 "Hey, Ugly!"
Rene represents a teenager in a medical malpractice suit; Mary Elizabeth and Colliar deal with the possibility that their daughter is sexually active.
S2, EP17 "From This Day On"
M.E. changes her will; Rene begins a relationship with a white man; young M.E. and Rene learn some shocking news.
S2, EP16 "HomeGirl"
Rene's (Lorraine Toussaint) friend from college causes a rift between her and Mary Elizabeth (Annie Potts).
