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After discovering that his late father has gone through most of the family fortune, Tod Stiles hits the title trans-America highway in his Corvette in search of adventure with friend Buz Murdock, a survivor of New York's mean streets. The two work odd jobs as they meet and interact with colorful characters and find themselves plunged into one situation after another, some of them romantic, some of them very dangerous. Later, Linc Case, a Vietnam war hero trying to find himself, takes over as Tod's travel companion.
S2, EP31 "Hell Is Empty, All the Devils Are Here"
Tod goes to work for a wild-animal park, whose owner (Peter Graves) plans revenge against the man he blames for his first wife's death.
S2, EP32 "From an Enchantress Fleeing"
Tod, in Southern California, is working for an ultra-successful female doctor who combines psychology and dentistry; he meets a shy inventor who creates an infallible love machine with his wife.
S3, EP1 "One Tiger to a Hill"
Tod and Buz, in Astoria, Ore., are working as crewmen on a fishing boat; a fisherman struggling with a trauma from his past makes a brutal, unprovoked attack on Tod.
S3, EP2 "Journey to Ninevah"
A man (Buster Keaton) who believes he is a jinx proves himself when his brother (Joe E. Brown) is wrongly arrested; guest John Astin.
S2, EP30 "A Feat of Strength"
A Hungarian wrestling champion must appear in a promoter's fake matches.
S2, EP29 "Between Hello and Goodbye"
Tod becomes involved in a psychological drama when he falls for a girl (Susan Oliver) he met in a nightclub; guest Herschel Bernardi.
