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After discovering that his late father has gone through most of the family fortune, Tod Stiles hits the title trans-America highway in his Corvette in search of adventure with friend Buz Murdock, a survivor of New York's mean streets. The two work odd jobs as they meet and interact with colorful characters and find themselves plunged into one situation after another, some of them romantic, some of them very dangerous. Later, Linc Case, a Vietnam war hero trying to find himself, takes over as Tod's travel companion.
S2, EP23 "Go Read the River"
A speedboat designer retreats into his work after his wife leaves him.
S2, EP24 "Even Stones Have Eyes"
Buz enrolls in a Texas rehabilitation center after a construction mishap leaves him blinded, possibly for life; guest Barbara Barrie.
S2, EP25 "Love Is a Skinny Kid"
A masked, young woman (Tuesday Weld) comes to a Texas town and announces memorial services for a long-dead girl; guest Cloris Leachman.
S2, EP26 "Kiss the Maiden, All Forlorn"
Tod and Buz, heading toward Dallas, stop to help a girl whose car has broken down; the three are kidnapped at gunpoint; the kidnappers are associates of a wanted embezzler who has come back to the U.S. to stop his daughter from becoming a nun.
S4, EP19 "This is Going to Hurt Me More Than it Hurts You"
Tod and Linc meet an oblivious millionaire who doesn't realize that women want him for his money.
S4, EP18 "Who in His Right Mind Needs a Nice Girl?"
Tod and Linc meet a librarian with a dark side in Daytona, Florida.
S4, EP17 "Cries of Persons Close to One"
Tod and Linc encounter a boxer named Tank who likes to drink.
S4, EP16 "Kiss the Monster, Make Him Sleep"
Linc stops a woman from committing suicide, and finds romance.
