S4, EP22 "I'll Be Your Shelter"
As a monster hurricane approaches New York, Bloom and the team scramble to put preparations in place; Max and Helen make plans for an intimate New York wedding; Iggy and Martin reach a crossroads; Reynolds finally makes contact with his father.
S4, EP21 "Castles Made of Sand"
When an elder care facility shuts down, New Amsterdam is forced to take in many new patients; Max struggles with his decision to head back to London; Reynolds takes his personal frustrations out on his department with near disastrous results.
S4, EP20 "Rise"
Max discovers the extent to which Dr. Fuentes' cuts are damaging New Amsterdam and decides it's now or never; Iggy takes an unconventional approach to reach a young patient; Reynolds and Wilder perform a risky, life-saving surgery on unborn twins.
S4, EP19 "Truth Be Told"
Max discovers a fatal flaw in Dr. Fuentes' scheme to purchase the UMI medical clinic, which could be her ultimate undoing; Bloom treats two high school students for life-threatening injuries and uncovers a dangerous situation.
S4, EP18 "No Ifs, Ands or Buts"
Max orchestrates a plan to get Dr. Fuentes terminated from New Amsterdam once and for all; Helen confronts her medical complication; Iggy helps two patients deal with a breakup, which forces him to consider his own marriage.
S4, EP17 "Unfinished Business"
The New Amsterdam team continues to deal with the consequences of its big night out; Max and Helen discuss options for their future; Martin finally learns Iggy's secret; Bloom helps Leyla avoid a life-changing situation.
S4, EP16 "All Night Long"
The New Amsterdam team goes out for a night of karaoke and drinking but must face the consequences at work the next day; Iggy helps a mysterious patient confront a past trauma; Reynolds and Dr. Malvo discuss their future; Leyla gives Bloom bad news.
S4, EP15 "Two Doors"
Max formulates a bold plan to help New Amsterdam before it's too late; Reynolds and Fuentes fight over the best way to handle a risky surgery; Wilder asks Dr. Castries for help with a terminal cancer patient; Iggy helps a father and son with trauma.
S4, EP14 "... Unto the Breach"
As the team gathers to mourn the loss of someone dear, Max and Helen realize the extent to which New Amsterdam has changed since they left; Bloom struggles with a big decision; Reynolds decides to take his concerns for his patients to a new level.
S4, EP13 "Family"
Max and Helen adjust to sharing their lives and their problems, including the challenge of Helen's mother; Bloom and Reynolds treat a family after their horrific car accident lands them in the ED; Iggy and Trevor reach a new understanding.
S4, EP12 "The Crossover"
Helen takes the reins at NHS Hampstead Hospital; Max gets creative to help a patient; Reynolds makes a decision about Malvo; Iggy and Bloom help their patients understand the underlying cause of their stress; Wilder employs unconventional techniques.
S4, EP11 "Talkin' Bout a Revolution"
Max and Sharpe settle happily into their new life in London; Dr. Fuentes takes over as medical director with disastrous effects; Bloom helps a patient who thinks he's cursed; Iggy develops a plan to get his psych patients gainfully employed.
S4, EP10 "Death Is the Rule. Life Is the Exception"
As Max and Sharpe prepare to depart for London, a deadly superbug hits the hospital and draws them back in; Leyla confronts Bloom about the secret she's been hiding; Iggy digs deep to help grieving parents confront the reality that their son is gone.
S4, EP9 "In a Strange Land"
Max takes drastic measures to help several undocumented immigrants after a fire destroys the church where they had sought refuge; Sharpe and Malvo assist a patient with a life-threatening condition; Reynolds is conflicted about his new position.
S4, EP8 "Paid in Full"
Max is faced with a wrenching decision when New Amsterdam falls prey to a massive ransomware attack.
S4, EP7 "Harmony"
Max and Bloom are shocked when a deadly ambulance crash reveals a dangerous plan; Fuentes pressures Iggy to take on patients; Sharpe realizes her cost cutting has adversely affected her department; Reynolds, Baptiste and Malvo try to reach an accord.
S4, EP6 "Laughter and Hope and a Sock in the Eye"
Dr. Reynolds and Dr. Malvo have a heart-to-heart with Dr. Baptiste; Max learns more about Sharpe when someone from her past resurfaces; Iggy plays referee between two patients and their families; Dr. Wilder reconsiders Max's offer to join the staff.
S4, EP5 "This Be the Verse"
Dr. Fuentes continues in her quest to remake the hospital in her vision; Max goes the extra mile to help a patient in need; Dr. Sharpe and Iggy find themselves at odds over a serious issue; Reynolds discovers the importance of personal obligations.
S4, EP4 "Seed Money"
Max struggles with a new fiscal reality at the hospital; Dr. Sharpe is on a mission to provide follow-up cancer screenings for patients before it's too late; Bloom grapples with Dr. Shinwari's new overnight schedule.
S4, EP3 "Same As It Ever Was"
Max advises a young student at a science fair but encounters legal complications with her brilliant invention; Bloom encourages Dr. Shinwari to be more aggressive in the ED; Iggy gets a lesson in humility; Brantley has a surprise for the staff.
S4, EP2 "We're in This Together"
Max and Sharpe go public with their relationship at the hospital; the team struggles to keep a handle on an overcrowded and understaffed ICU and everyone must pitch in; Iggy's overly critical feedback alienates his residents.
S4, EP1 "More Joy"
Max and Sharpe wake up to a new, more personal dynamic; Iggy calls upon an old contact to help with an explosive situation; Bloom begins a tricky dynamic with her new Emergency Department residents; Reynolds finds himself in an awkward position.