
Defense attorney Perry Mason defends dozens of falsely accused people over the course of this long-running courtroom drama, and he manages to clear each and every one of them, usually by drawing out the real criminal on the witness stand. He is capably assisted by investigator Paul Drake and secretary Della Street, and is a continual thorn in the side of District Attorney Hamilton Burger.

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A fight for control of corporate voting stock results in murder, and Perry's client was at the scene of the crime.
Perry volunteers to defend a down-and-out man (Fred Sherman) charged with robbery and the murder of a dance-hall girl.
Perry defends a woman (Josephine Hutchinson) who confessed to the murder for which she is being tried; guest Ruta Lee.
An elderly woman retains Perry when she feels her employer is about to be murdered, a crime for which she is later arrested.