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Defense attorney Perry Mason defends dozens of falsely accused people over the course of this long-running courtroom drama, and he manages to clear each and every one of them, usually by drawing out the real criminal on the witness stand. He is capably assisted by investigator Paul Drake and secretary Della Street, and is a continual thorn in the side of District Attorney Hamilton Burger.
S1, EP35 "The Case of the Lazy Lover"
An unexplained $2,500 check in Perry's mail leads him to eventually defend its sender on a murder charge; guest Yvonne Craig.
S1, EP22 "The Case of the Fugitive Nurse"
Perry's client, a woman who retained him on a tax matter, finds herself charged with the fatal poisoning of her husband.
S1, EP23 "The Case of the One-Eyed Witness"
Perry's client in a blackmail payoff is charged with a double murder he believes she did not commit; guest Angie Dickinson.
S1, EP24 "The Case of the Deadly Double"
Perry is retained to defend a client on a homicide charge before the murder takes place; guests Constance Ford, Denver Pyle.
S5, EP6 "The Case of the Meddling Medium"
An elaborate electrical device in the courtroom proves Perry's point about a murder in a booby-trapped elevator.
S5, EP5 "The Case of the Crying Comedian"
A comedian tries to take blame for a murder to protect an innocent girl; guests Sue Ane Langdon, Jackie Coogan.