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Emergency room nurse Jackie Peyton does everything she can to provide her patients with the best care possible while navigating the waters of a crumbling health-care system. But she has a secret that is increasingly difficult to keep from people -- she relies on Vicodin and Adderall to get her through high-stress shifts at a New York hospital, where she isn't above bending the rules to keep things running smoothly in the face of indifferent doctors, penny-pinching bean counters and miles of bureaucratic red tape.
S1, EP12 "Health Care and Cinema"
Kevin invites Jackie to a midnight rendezvous; the movie critic wakes; Eddie learns the truth about Jackie's family; O'Hara's mother is admitted.
S2, EP1 "Comfort Food"
Jackie tries to reconnect with her family; Coop lodges a complaint.
S2, EP6 "Bleeding"
Jackie asks Eddie to end his friendship with Kevin; a pharmaceutical company rep serves Jackie's needs; O'Hara's romance heats up.
S2, EP7 "Silly String"
The hospital's biggest donor is insulted by Coop; Jackie reconsiders her affair with Eddie.
S4, EP9 "Are Those Feathers?"
Grace refuses to attend school; Jackie seizes control of the E.R.; Cruz suffers a pulmonary episode.
S4, EP8 "Chaud & Froid"
Cruz takes revenge on Jackie's coworkers; Eddie supports Jackie's case; Lenny intends to move to Europe; O'Hara leans on Coop.
S4, EP7 "Day of the Iguana"
Jackie covers for Cruz; Jackie's lawyer advises her to be tough; Zoey surveys her co-workers; Akalitus asks the staff to participate in an elaborate charade.
S4, EP6 "No-Kimono-Zone"
Jackie has a dream about Cruz and using; Coop becomes insistent about involvement with O'Hara's child; Zoey questions her feelings for Lenny; O'Hara takes action.