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Emergency room nurse Jackie Peyton does everything she can to provide her patients with the best care possible while navigating the waters of a crumbling health-care system. But she has a secret that is increasingly difficult to keep from people -- she relies on Vicodin and Adderall to get her through high-stress shifts at a New York hospital, where she isn't above bending the rules to keep things running smoothly in the face of indifferent doctors, penny-pinching bean counters and miles of bureaucratic red tape.
S1, EP10 "Ring Finger"
Jackie uses an unusual ploy to get Coop off her back; O'Hara helps Jackie remove her wedding ring; Jackie begins mother-daughter dance lessons with Grace.
S1, EP11 "Pill-O-Matix"
Eddie is replaced by a machine; Zoey administers the wrong dose of a painkiller; parents come forward to claim the baby that Akalitus is caring for.
S1, EP12 "Health Care and Cinema"
Kevin invites Jackie to a midnight rendezvous; the movie critic wakes; Eddie learns the truth about Jackie's family; O'Hara's mother is admitted.
S2, EP1 "Comfort Food"
Jackie tries to reconnect with her family; Coop lodges a complaint.
S6, EP9 "Candyman"
Frank warns Jackie about an upcoming DEA investigation at the hospital; Antoinette turns to Eddie for help; Coop and Carrie look for loopholes; a death causes the staff to reflect.
S6, EP8 "The Lady With the Lamp"
Jackie goes through detox at home with help from her friends; a dream patient exposes a great fear; Frank objects to Grace's moving back home.
S6, EP7 "Rat on a Cheeto"
Jackie wants to get sober after Antoinette's startling confession; Jackie finds drugs in Grace's room; Akalitus names Zoey "Nurse of the Month"; Coop's dream comes true.
S6, EP6 "Nancy Wood"
Jackie's fake identity is compromised; Frank moves in; Antoinette badgers Jackie about her sobriety; Prentiss plans a night out with Zoey.