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At fictional Princeton Plainsboro Teaching Hospital in New Jersey, prickly genius Dr. Gregory House tackles health mysteries as would a medical Sherlock Holmes, all the while playing mind games with colleagues that include his best friend, oncologist James Wilson. House, an acerbic infectious disease specialist, solves medical puzzles with the help of a team of young diagnosticians. Flawless instincts and unconventional thinking help earn House great respect, despite his brutal honesty and antisocial tendencies.
S2, EP1 "Acceptance"
When death row inmate Clarence mysteriously collapses after hallucinating, House jumps at the case for its difficulty and because he thinks it is "cool."
S2, EP2 "Autopsy"
A 9-year-old patient with terminal cancer handles her situation so well that House begins to wonder whether she is really that brave or if it is a medical symptom.
S2, EP3 "Humpty Dumpty"
When Cuddy's handyman, Alfredo, falls from her roof and develops strange symptoms, she joins the team to figure out what is wrong with him.
S2, EP4 "TB or Not TB"
The hospital admits a renowned physician and advocate against the spread of tuberculosis in Africa, and his TB-like symptoms draw media attention which could further his cause.
S1, EP22 "Honeymoon"
While House works to save Stacy's husband, he cannot help but think his feelings for her may have reignited.
S1, EP21 "Three Stories"
A woman from Dr. House's past returns to the hospital, where she used to be legal counsel, seeking his help in diagnosing the illness her husband has.
S1, EP8 "Poison"
House and his team investigate the mysterious poisoning of a high-school student, and they think they have the answers they need until a second teen develops the same symptoms.
S1, EP7 "Fidelity"
When a young housewife falls ill, House suspects that she has contracted a rare sexually transmitted disease, but she and her husband, Dominic Purcell, each deny having an affair.