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Mystery writer and amateur detective Jessica Fletcher - a down-to-earth, middle-aged widow - ferrets out the criminals in idyllic Cabot Cove, Maine, which apparently is the murder capital of the United States for the show's 12-season run. Though while traveling, she uncovers a fair number of killers as well.
S4, EP12 "Who Threw the Barbitals in Mrs. Fletcher's Chowder?"
Shortly after Sheriff Tupper's sister leaves her husband and seeks refuge in Cabot Cove, a murder occurs.
S4, EP13 "Harbinger of Death"
An unhappy wife, a government official, a lovesick assistant and a self-centered astronomer are suspects in the murder of a young executive.
S4, EP14 "Curse of the Daanau"
When Seth's estranged brother is murdered, Jessica must figure out if a cursed ruby from India is responsible.
S4, EP15 "Mourning Among the Wisterias"
When Jessica visits a celebrated playwright friend, she encounters murder and an unexpected marriage proposal.
S12, EP7 "Nan's Ghost"
Jessica escapes from the dungeon and works with Inspector Lanahan to uncover the killer of an American investor.
S12, EP6 "Nan's Ghost"
Jessica's investigation into ghost stories lands her in the dungeon.
S12, EP5 "Home Care"
After losing two elderly patients, a young nurse (Megan Porter Follows) is found holding a syringe containing poison and charged with murder.
S12, EP4 "Big Easy Murder"
A research trip to New Orleans plunges Jessica into the world of the occult, when a businessman dies, and a voodoo doll is evidence.
