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Mystery writer and amateur detective Jessica Fletcher - a down-to-earth, middle-aged widow - ferrets out the criminals in idyllic Cabot Cove, Maine, which apparently is the murder capital of the United States for the show's 12-season run. Though while traveling, she uncovers a fair number of killers as well.
S10, EP5 "A Virtual Murder"
Jessica happens on a computerized clue to a murder while writing a mystery story for a friend's interactive video game company.
S10, EP6 "Bloodlines"
Researching a novel, Jessica unravels the mystery of a Thoroughbred trainer's (Mickey Rooney) murder.
S12, EP7 "Nan's Ghost"
Jessica escapes from the dungeon and works with Inspector Lanahan to uncover the killer of an American investor.
S12, EP8 "Shooting in Rome"
Jessica travels to Rome to help rewrite the script for the filming of one of her books, but the filming takes a tragic turn when a stuntman dies.
S12, EP6 "Nan's Ghost"
Jessica's investigation into ghost stories lands her in the dungeon.
S12, EP5 "Home Care"
After losing two elderly patients, a young nurse (Megan Porter Follows) is found holding a syringe containing poison and charged with murder.
S12, EP4 "Big Easy Murder"
A research trip to New Orleans plunges Jessica into the world of the occult, when a businessman dies, and a voodoo doll is evidence.
S12, EP3 "The Secret of Gila Junction"
Jessica helps an inexperienced sheriff investigate a murder in a small desert town where the government may have conducted dangerous chemical experiments.