
Fun-loving San Francisco Police Department investigator Nash Bridges is part of the elite Special Investigations Unit. He tackles crime using his keen sense of humor and charm. Joe Dominguez comes out of retirement to become Bridges' wisecracking yet more rule-abiding partner.

Nash sets out to help Lisa, whose eyewitness account of a murder raises some eyebrows when no body can be found; Joe checks out his new investment.

Nash must clear his name after being suspended following an Internal Affairs accusation that he murdered a suspect in revenge.

Joe is exposed to a deadly virus after a thief unwittingly releases it into the air while foraging for drugs at a chemical lab.

Nash's daughter, Cassidy, is kidnapped by an escaped anti-government extremist who is out to avenge his imprisonment and separation from his family.