
Dr. Mark Sloan is chief of Internal Medicine at Community General Hospital -- and sometime consultant to the local police department. When he's drawn into a case, he combines sleuthing and medicine to solve the crime. That crime is usually one his detective son, Steve, is working on as a member of the local police department. Dr. Sloan's medical colleagues, including doctors Amanda Bentley, Jack Stewart and Jesse Travis, are also frequently drawn into his investigations.

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Mark (Dick Van Dyke) is targeted in a murder plot after discovering too much about the death of a plastic surgeon. With Scott Baio.
Agents from the National Security Agency arrive at the hospital after Amanda is attacked by a man she was preparing to autopsy.
Jesse disappears from a mountain cabin for five days and resurfaces in Utah, claiming to have been abducted by aliens.
Dr. Sloan is less than thrilled to have his sister move in after the police discover a body in the closet of her new home.