
Dr. Mark Sloan is chief of Internal Medicine at Community General Hospital -- and sometime consultant to the local police department. When he's drawn into a case, he combines sleuthing and medicine to solve the crime. That crime is usually one his detective son, Steve, is working on as a member of the local police department. Dr. Sloan's medical colleagues, including doctors Amanda Bentley, Jack Stewart and Jesse Travis, are also frequently drawn into his investigations.

The shooting death of a patient opens a doorway to Mark's past that forces him to face the disappearance of his father.

Mark attempts to discover why his father, a former police detective, vanished more than 50 years earlier, leaving him and his mother to fend for themselves.

Dr. Sloan investigates the demise of a television star who may have died because of compulsive dieting.

When a big-time bookie and a gambling heart surgeon turn up dead, Mark bets that something foul is afoot.