
Tom Selleck stars as Frank Reagan, the New York Police Commissioner, and patriarch of the Reagan clan, a multigenerational family of cops. Frank's oldest son is Danny, a seasoned detective and Iraqi War veteran who occasionally uses dubious tactics to solve cases. Daughter Erin, the lone female, is an assistant district attorney. Fresh out of Harvard Law, Jamie is the youngest member and "golden boy" of the family. Jamie gave up a lucrative future in law to continue the family's tradition in police work, and is asked to participate in a secretive investigation that even his father does not know about.

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Soon after Frank honors a detective with an award for his undercover work in Malaysia, the detective is captured by a Malaysian drug lord; Henry accompanies Jamie on a ride-along.

Erin asks Danny to protect her key witness, a notorious photographer, after a nearly fatal hit-and-run accident; Vinny and Jamie go after a drug operation.

When a man is stabbed by an attacker dressed as the spirit of death, Danny investigates a voodoo community; Garrett tells Frank about a dark secret; Nicky and Erin take Jack and Sean trick-or-treating.

Danny finds a murdered student at a college campus; after reconnecting with a former law-school classmate, Jamie has a life crisis; Erin tries to give Nicky some freedom.