
An elite squad of FBI profilers analyzes the country's most-twisted criminal minds, anticipating the perpetrators' next moves before they can strike again. Each member of the "mind hunter" team brings his or her expertise to pinpoint predators' motivations and identify emotional triggers to stop them. The core group includes an official profiler who is highly skilled at getting into the minds of criminals, a quirky genius, the former media liaison who manages to adeptly balance family life and the job, and a computer wizard.

The team tracks a serial killer when remains of numerous victims are found in the walls of an elderly couple's home; the hunt becomes urgent after the BAU learns the killer's specific ritual of when to strike; Rossi reconnects with his ex-wife.

Packages with gruesome contents are delivered to six people in the Washington, D.C. area; Simmons and Kristy struggle to connect with their son, David, who is suspended from school for aggressive behavior.

The BAU meets in secret to investigate a subject who appears to be kidnapping and photographing young women.

Elizabeth Prentiss, a foreign ambassador and SSA Emily Prentiss' mother, seeks the aid of the BAU when a Russian immigrant is kidnapped.