After bringing in a complicated spinal surgery, Dr. Aaron Glassman challenges the residents for an opportunity to join him in the operating room; Shaun and Morgan disagree on how to treat a comatose patient with a cancerous tumor.

When the hospital is hit with a cyberattack, threatening to shut down life-saving machines, Lea rises to the challenge and looks to outsmart the hackers to prove herself; the team treats an inspirational cancer survivor who harbors a dark secret.

Lim is challenged by the unique circumstances surrounding a pregnant patient with an aggressive tumor; after misdiagnosing a patient, Claire makes a disconcerting discovery about certain practices at the hospital.

The team treats a teenage gymnast who experiences complications from her intensive training; Shaun meets Lea's parents for the first time.

Dr. Morgan Reznik discovers her patient's wealth and obsession with extending his life is a dangerous mix that could end up costing more than he can afford.

Dr. Audrey Lim struggles to cope with the residual emotional trauma of COVID-19; Dr. Claire Browne suggests a radical treatment to help a war veteran who has PTSD; Dr. Shaun Murphy declares he doesn't want to teach the new residents anymore.

Dr. Murphy questions his decision to give the new residents autonomy when an intern's misdiagnosis has dire consequences; a patient has a ruptured cyst affecting key functions of her brain; Dr. Morgan Reznick and Park bond over failed relationships.

Morgan and Shaun's pregnant patient with twins has pain, forcing the doctors to grapple with a decision no one wants to make; Shaun asks Lea to move back in despite her reservations.

With several candidates vying for residency at St. Bonaventure, Lim tasks Shaun, Claire and Alex with mentoring the top first-year resident contenders; Shaun inadvertently insults Lea while discussing the pros and cons of a controversial surgery.