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Joe Mannix is a Los Angeles-based detective who ends up taking a lot of punishment. When the show starts, he works for a large L.A. detective agency, Intertect. But beginning in season two, he sets out on his own and becomes a private investigator, assisted by loyal secretary Peggy Fair, the widow of a police officer. In the course of solving crimes, he can be expected to be shot, beaten, knocked unconscious, driven off the road or similarly injured. But despite all the bodily trauma, Mannix always gets his man.
S6, EP21 "Search for a Whisper"
A prospective candidate (William Shatner) asks Mannix to find anything his political enemies could use against him; guest Susan Flannery.
S6, EP22 "To Quote a Dead Man"
A hobo (David Wayne) becomes the target of gunmen every time he puts on his patchwork coat; guests Lloyd Bochner, Barbara Babcock.
S6, EP23 "A Problem of Innocence"
The daughter (Anne Archer) of a businessman imprisoned for stealing a payroll hires Mannix to investigate her father's mysterious death.
S6, EP24 "The Danford File"
A blackmailer threatens to expose the unsavory past of a politician's wife (Jessica Walter); guests John Gavin, Milt Kamen.
S6, EP19 "Carol Lockwood -- Past Tense"
The investigation of his former girlfriend's death leads Mannix to a tycoon (Jason Evers) and a woman pilot; guest Joanna Miles.