
Dr. Richard Kimble is wrongly convicted for the murder of his beloved wife. Kimble, determined to track down the real killer, escapes from custody following a train crash while being transported to death row. What follows is a game of cat-and-mouse -- for both the true murderer and the good doctor. But while Kimble searches for the real killer, the authorities -- notably Lt. Philip Gerard -- are on the hunt for him.

To catch an embezzler, a police officer (Charles Bronson) boards a yacht where Kimble is working; guest Anne Francis.

Kimble interferes with a woman's (Celeste Holm) search for evidence against a shady construction boss; guests Jack Warden, Harold Gould.