
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

Autopsies reveal that a string of unexplained deaths in Omaha resulted from poison-induced liver disintegration.

Wealthy man is shot dead while his wife is forced to open their hidden safe, but they couldn't be identified because they were wearing ski masks.

After the discovery of a skull in the forest near a boy scout camp, police use facial reconstruction to identify the body.

The bomb was constructed to cause as much damage as possible, and it did, killing the victim with deadly force and flame; a painstaking search yielded tiny clues, which identified the killer as surely as if he'd signed them.