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Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.
S10, EP23 "A Clean Getaway"
An anonymous caller reports the rape and murder of a dry cleaner employee; two eyewitnesses tell two similar but not identical stories.
S9, EP2 "Hunter or Hunted?"
A woman's apparent accidental death begins to look fishy after police uncover a letter written by the victim days before her untimely death.
S2, EP7 "Fatal Fungus"
When dozens of infants develop serious breathing problems in the Cleveland area, doctors and investigators search high and low for the cause.
S12, EP26 "Driven to Silence"
After 10 years, a witness decides to do the right thing about the rape and murder of a young hairdresser.
S14, EP21 "Expert Witness"
A killer assaults a young mother in her home, but despite meticulous washing of the crime scene, a single hair remains to lead authorities to the culprit.
S14, EP20 "Funeral Services"
Police discover a mask near the crime scene and hope that it leads to the killer of a funeral director.
S14, EP19 "Skeleton Key"
A woman goes missing for a month with the only clues being a set of keys, a fingerprint and a code.
S14, EP17 "Seeing Red"
A body is found stuffed into a suitcase forcing the police to search though the landfill for another missing victim.