
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A nosy neighbor with a disturbing obsession becomes a suspect in a woman's murder at an upscale apartment complex; police discover an incredible link to an unrelated murder thousands of miles away.

A dismembered body is dumped on the side of the New Jersey Turnpike and before police realize it, bodies are turning up between two states.

A DNA dragnet catches a killer eight years after the kidnapping, rape and murder of a college coed in Oklahoma.

Tara Munsey went missing after a work shift at a Virginia restaurant, and it is unknown if she ran away or if she was the victim of foul play.