
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A woman is found dead, police use blood evidence and computer forensics to convince a jury that the murderer is guilty.

A new life-insurance policy sparks suspicions of murder when a Nova Scotia schoolteacher's body is found at the bottom of her basement stairs.

When an elderly woman dies in an apparent robbery-homicide, evidence suggests the suspect broke out of the house rather than breaking in.

Autopsies reveal that a string of unexplained deaths in Omaha resulted from poison-induced liver disintegration.