
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A death in Pennsylvania is strikingly similar to one in North Carolina.

When a policeman's home burns to the ground, he later arrests a man who confesses to arson, but the confession seems dubious.

Technology able to analyze human bite-marks yields information on a woman's death.

A woman identifies her husband as her attacker, but questions arise 16 years later regarding her recollections.