
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

Fingerprints taken from a piece of cloth help solve the rape and murder of a 22-year-old woman in Henrico County, Va.

When a human skeleton is found on marshland and determined to be at least 18 months old, a computer consultant gives her a face and name.

A cunning serial rapist who leaves no decisive evidence forces investigators to rely on geographical profiling in their search for an identity; DNA from a cigarette butt may provide the final piece of evidence needed to catch the suspect.

A killer places all the incriminating evidence to the murder in a plastic bag, hoping it will float down the river.