
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

New York police hunt the Zodiac killer after a series of deadly attacks.

When a healthy young man dies mysteriously in his sleep, toxicology tests reveal that it may have been foul play. Could a "suicide note" hold the key to solving the case?

Investigators weigh several theories while probing the death of a retired police officer, including a botched robbery and suicide.

The bodies of two young women are found in the ashes of an apartment fire.