
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

When a single mother is murdered, her brother vows to find the person responsible for the death of his sister, even if it takes more than 30 years.

Photographs found in a dumpster lead to the killer of Los Angeles model Linda Sobek; the man claims he did not intentionally kill her despite evidence to the contrary.

A husband and wife get shot, and their 16-year-old daughter manages to escape, but investigators suspect she may be involved in the murder.

The FBI profiles a suspect in the kidnapping and murder of a 6-year-old girl during an evening church service; a witness leads authorities to the likely killer, but then becomes a victim herself.