
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A mother puts her hope on the internet and an independent investigation to clear her name after authorities charge her with murdering her 17-month-old son in a fire considered to be intentionally set.

In 1984 police failed to convict the murderer of a college student; new technology may finally help the police to catch her killer.

A murder mystery theater performance in Easton, Md., turns into a real-life mystery when a body is found after the performance ends.

Police investigate a young woman found murdered two weeks after reporting a road rage incident; evidence leads not to the aggressive driver, but one of their own.