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Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.
S6, EP18 "Bad Blood"
When a young doctor is accused of sedating and sexually assaulting two of his female patients, DNA tests show him to be innocent, but the women persist with their claims; seven years later, a private investigation leads to a surprising discovery.
S8, EP9 "Breaking News"
A search in Virginia's DNA databank reveals the identity of a news producer's murderer.
S13, EP9 "Home Evasion"
A shooting victim mutters the name of her apparent assailant before dying, but fingerprint comparisons, handwriting analysis, ballistics and DNA testing show someone else close to home is the true killer.
S6, EP10 "Church Disappearance"
The FBI profiles a suspect in the kidnapping and murder of a 6-year-old girl during an evening church service; a witness leads authorities to the likely killer, but then becomes a victim herself.
S14, EP21 "Expert Witness"
A killer assaults a young mother in her home, but despite meticulous washing of the crime scene, a single hair remains to lead authorities to the culprit.
S14, EP20 "Funeral Services"
Police discover a mask near the crime scene and hope that it leads to the killer of a funeral director.
S14, EP19 "Skeleton Key"
A woman goes missing for a month with the only clues being a set of keys, a fingerprint and a code.
S14, EP17 "Seeing Red"
A body is found stuffed into a suitcase forcing the police to search though the landfill for another missing victim.