
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.
The light of day and DNA picture painted by molecular biologist reveals new clues about a nighttime traffic accident.
After a tycoon's wife is found dead in her SUV submerged in a half-frozen creek, police begin to suspect it wasn't an accident.
On Valentine's Day, an obstetrician finds his wife dead and calls 911; police discover inconsistencies between the blood spatter evidence and his version of events.
A killer tried to destroy everything which could link them to the crime; but in doing so, they inadvertently created new forensic evidence, evidence which came to light using a technique never before used in a criminal investigation.