
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A trio of men, responsible for several bank robberies, leaves no evidence behind; forensic scientists help catch them by looking at the criminals' posture and clothing.

A jeweler's search through old sales records helps police find likely suspects in the murder of elderly couple Edward Kowalzck and Gertrude Thompson.

Haunted by her mother's long-ago disappearance, a woman undertakes an investigation of her own and stumbles upon a dark family secret.

A garbage bag leads police to a child's killer.