
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A young college student is found dead in her apartment and the autopsy rules the death a homicide by an unknown male suspect.

When detectives find a mismatched button in relation to a woman's death, they know they can follow the clue back to the killer.

The killer removed the computer that links him to the murder of a woman and her soon-to-be ex-husband that he had met online.

A family break turns into a nightmare when the wife is found face-down in a lake; with no idea whether it was murder, an accident or suicide, police turn to a new forensic technique.