
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A murder mystery theater performance in Easton, Md., turns into a real-life mystery when a body is found after the performance ends.

When a woman dies in a horseback riding accident, police uncover a web of lies in her husband's background after his suspicious behavior prompts a closer look.

A serial killer in Tampa, Fla., taunts police by strangling prostitutes and leaving their bodies in plain sight, but tire marks and fibers lead to the culprit.

A killer wants to outwit the police and keep the identity of his victim secret so he removes the teeth; however, lab tests on the skull reveal not just the horrific nature of the murder, but the identity of the victim too.