
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

After a tycoon's wife is found dead in her SUV submerged in a half-frozen creek, police begin to suspect it wasn't an accident.

A young man is killed in a mysterious car crash, but the evidence at the scene lead investigators to believe it is not an accident; forensic science reveals what really happens, and the truth devastates three families.

A Russian immigrant is found dead and a strange phone call to his office is the only lead investigators have.

A decade old case reopens, and a few seconds of a 911 call enable investigators to determine who is responsible for a murder.