
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

Romanian archbishop Valerian D. Trifa, living in the U.S., is accused of being a Nazi war criminal, and forensic experts find evidence on an incriminating, 40-year-old postcard.

Teenager is found half-naked with her throat slit; a single foreign hair found on her thumb may finger the killer.

Investigators look into the shooting death of Russ Stager, a popular gym teacher, and discover that his death was not an accident; a message the victim recorded before his death reveals a story of greed.

A bullet-riddled car, a missing driver, and no witnesses, an ambush or a random attack; the clue was something so tiny, it was measured in millionths of a meter.