
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A flawed envelope is an unlikely clue to identifying a killer who laced a water cooler with cyanide and caused the death of a woman.

Detectives find suspicious similarities when a husband and wife report their second daughter missing a few years after the disappearance of their first.

A mussel diver and his fiancée are found dead in their burnt home; a tiny clue points to arson and murder.

Police exhume the body of Karla Brown, murdered in her home in 1978, to study bite wounds, which eventually lead to the killer.