
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A random serial sniper is plaguing Virginia and Maryland, with no profile of their victims.

A serial arsonist burns thousands of California homes and businesses.

A woman wins her release after being imprisoned for allegedly killing her mother in a car fire.

While investigating the case of a Colorado hunter shot three times and killed, police suspect two murder weapons, and two killers, but forensic evidence points them closer to home.