
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

Experts debate whether an apparent heart attack victim died from natural causes or alleged poisoning by his girlfriend.

After a Vancouver custodian finds a burned body in a dumpster, investigators determine the corpse's identity and attacker.

When 15 year-old Marlene Miller was murdered, it would take 24 years and several retrials before forensic scientists discovered the evidence to bring her killer to justice.

When dozens of infants develop serious breathing problems in the Cleveland area, doctors and investigators search high and low for the cause.